Newman Jared M, George Jaiben, Klika Alison K, Barsoum Wael K, Higuera Carlos A
Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH.
Am J Orthop (Belle Mead NJ). 2017 Sep/Oct;46(5):E308-E313.
Periprosthetic joint infection (PJI) is a serious and potentially devastating complication of total joint arthroplasty. Accurate diagnosis of PJI is of utmost importance, but differentiating septic from aseptic failed total joint arthroplasty is extremely challenging, and improper management can lead to significant morbidity. The gold standard for PJI diagnosis is based on standardized laboratory and clinical criteria but relies on preoperative and intraoperative findings, which can be unreliable. Given these limitations, research has focused on new methods for diagnosing PJI. Synovial fluid inflammatory cytokines have been found to accurately diagnose PJI. In this article, we review the synovial fluid cytokines that are being used as aids in PJI diagnosis.
人工关节周围感染（PJI）是全关节置换术一种严重且可能具有毁灭性的并发症。准确诊断PJI至关重要，但区分感染性与无菌性全关节置换失败极具挑战性，且管理不当会导致严重的发病率。PJI诊断的金标准基于标准化的实验室和临床标准，但依赖于术前和术中的发现，而这些发现可能并不可靠。鉴于这些局限性，研究集中在诊断PJI的新方法上。已发现滑液炎症细胞因子可准确诊断PJI。在本文中，我们综述了用作PJI诊断辅助手段的滑液细胞因子。
