小阴茎与先天性肾上腺发育不全。
Micropenis and congenital adrenal hypoplasia.
作者信息
Bourgeois M J, Jones B, Waagner D C, Dunn D
机构信息
Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock 79430.
出版信息
Am J Perinatol. 1989 Jan;6(1):69-71. doi: 10.1055/s-2007-999548.
Micropenis is often an early sign of congenital hypopituitarism. It has also been associated with congenital adrenal hypoplasia in infants with anencephaly and pituitary agenesis. This report is on two infants with micropenis and congenital adrenal hypoplasia. One presented with a similar clinical course and postmortem findings to previously reported cases of adrenal hypoplasia and pituitary agenesis. The other patient represents the first reported case of an infant with micropenis and congenital adrenal hypoplasia in the absence of pituitary agenesis. The histologic patterns of adrenal hypoplasia, as well as the etiologic and clinical implications of its association with micropenis, are discussed.
小阴茎通常是先天性垂体功能减退的早期迹象。它也与无脑儿和垂体发育不全婴儿的先天性肾上腺发育不全有关。本报告介绍了两名患有小阴茎和先天性肾上腺发育不全的婴儿。其中一名婴儿的临床病程和尸检结果与先前报道的肾上腺发育不全和垂体发育不全病例相似。另一名患者代表了首例报道的无垂体发育不全的小阴茎和先天性肾上腺发育不全婴儿病例。本文讨论了肾上腺发育不全的组织学模式及其与小阴茎关联的病因学和临床意义。
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