Bautista D V, Asch M, Kovacs K, Murray D
Department of Pathology, St. Michael's Hospital, University of Toronto, Ont.
Can J Surg. 1989 Jan;32(1):51-5.
The authors describe three cases of adrenal myelolipoma. In the first two, unilateral adrenal masses, assumed to represent adrenal neoplasms, were found during urologic examination; the correct diagnosis was made by frozen-section examination during operation. The third case involved bilateral adrenal lesions diagnosed at autopsy in a patient suspected to have metastatic cancer. Histologic, immunohistochemical and electron microscopic studies revealed polyclonal lesions composed of hematopoietic cells and fat cells. Radiologic recognition and fine-needle biopsy of these lesions are important to avoid unnecessary surgery in asymptomatic cases. Since the lesions cannot be regarded as true neoplasms, the authors suggest that the name myelolipoma should be replaced by the term myelolipomatous nodule.
作者描述了三例肾上腺髓脂肪瘤。在前两例中，在泌尿外科检查时发现单侧肾上腺肿块，推测为肾上腺肿瘤；术中通过冰冻切片检查做出了正确诊断。第三例是在一名疑似患有转移性癌症的患者尸检时诊断出双侧肾上腺病变。组织学、免疫组织化学和电子显微镜研究显示，病变由造血细胞和脂肪细胞组成，为多克隆性。对这些病变进行放射学识别和细针活检，对于避免无症状病例进行不必要的手术很重要。由于这些病变不能被视为真正的肿瘤，作者建议将髓脂肪瘤这个名称替换为髓脂肪瘤样结节。
