耐碳青霉烯鲍曼不动杆菌在新生儿重症监护病房的克隆传播。
Clonal spread of carbapenem-resistant Acinetobacter baumannii in a neonatal intensive care unit.
机构信息
Laboratório de Pesquisa em Ciências da Saúde, Universidade Federal da Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
Laboratório de Pesquisa em Ciências da Saúde, Universidade Federal da Grande Dourados, Dourados, Mato Grosso do Sul, Brazil; Fundação Osvaldo Cruz, Campo Grande, Mato Grosso do Sul, Brazil; Hospital Universitário de Dourados, Universidade Federal da Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
出版信息
J Hosp Infect. 2018 Mar;98(3):300-304. doi: 10.1016/j.jhin.2017.10.015. Epub 2017 Oct 26.
Acinetobacter baumannii has often been associated with colonization and/or infection in neonatal intensive care units (NICU). This study describes a clonal spread of carbapenem-resistant A. baumannii (CRAB) isolates in an NICU. In total, 21 CRAB isolates were collected from premature newborns. Only polymyxin B was active against such isolates. Nineteen CRAB isolates were clonally related (Cluster C, which belonged to worldwide-disseminated ST1). All newborns had peripheral access and had received β-lactam therapy previously. The implementation of strict infection control measures was of fundamental importance to eradicate the clonal type in the study hospital.
鲍曼不动杆菌常与新生儿重症监护病房（NICU）的定植和/或感染有关。本研究描述了 NICU 中碳青霉烯类耐药鲍曼不动杆菌（CRAB）分离株的克隆传播。共从早产儿中收集了 21 株 CRAB 分离株。只有多粘菌素 B 对这些分离株有效。19 株 CRAB 分离株具有克隆相关性（聚类 C，属于全球传播的 ST1）。所有新生儿均有外周通路，且此前均接受过β-内酰胺类治疗。实施严格的感染控制措施对于在研究医院根除该克隆类型至关重要。
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