Struk S, Honart J-F, Qassemyar Q, Leymarie N, Sarfati B, Alkhashnam H, Mazouni C, Rimareix F, Kolb F
Department of Plastic Surgery, Gustave-Roussy, 114, rue Edouard-Vaillant, 94800 Villejuif, France.
Department of Plastic Surgery, Gustave-Roussy, 114, rue Edouard-Vaillant, 94800 Villejuif, France.
Ann Chir Plast Esthet. 2018 Feb;63(1):54-61. doi: 10.1016/j.anplas.2017.09.008. Epub 2017 Oct 26.
The Indocyanine green (ICG) is a soluble dye that is eliminated by the liver and excreted in bile. When illuminated by an near-infrared light, the ICG emits fluorescence in the near-infrared spectrum, which can be captured by a near-infrared camera-handled device. In case of intravenous injection, ICG may be used as a marker of skin perfusion. In case of interstitial injection, it may be useful for lymphatic network mapping. In oncological and reconstructive breast surgery, ICG is used for sentinel lymph node identification, to predict mastectomy skin flap necrosis, to assess the perfusion of free flaps in autologous reconstruction and for diagnosis and treatment of upper limb secondary lymphedema. Intraoperative indocyanine green fluorescence might also be used to guide the excision of nonpalpable breast cancer.
吲哚菁绿（ICG）是一种可溶性染料，由肝脏清除并经胆汁排泄。当受到近红外光照射时，ICG会在近红外光谱中发出荧光，可被近红外摄像设备捕捉。静脉注射时，ICG可用作皮肤灌注的标志物。间质注射时，它可用于淋巴管网络测绘。在肿瘤学和乳房重建手术中，ICG用于前哨淋巴结识别、预测乳房切除皮瓣坏死、评估自体重建中游离皮瓣的灌注情况以及上肢继发性淋巴水肿的诊断和治疗。术中吲哚菁绿荧光还可用于指导不可触及乳腺癌的切除。
