Kelly J K, Denier J E, Wilner H I, Lazo A, Metes J J
Department of Radiology, Harper Hospital, Detroit, MI 48201.
J Comput Assist Tomogr. 1989 Jan-Feb;13(1):27-9.
The authors present two patients with Paget disease, both showing lytic changes in the calvarium. On T1 contrast sequences, the first patient demonstrated an extraaxial soft tissue mass in the temporooccipital region. This abnormality was hypointense to the adjacent normal diploic tissue. The second patient demonstrated a hypointense frontal abnormality on the T1-weighted sequence. Intracranial extension of this lesion was associated with lysis in otherwise mixed signal pagetoid bone. The first patient had osteoclastic Paget disease or osteoporosis circumscripta. The second patient had sarcomatous degeneration.
作者介绍了两名患有佩吉特病的患者，两人均表现出颅骨的溶骨性改变。在T1加权对比序列上，第一名患者在颞枕区显示一个轴外软组织肿块。该异常相对于相邻正常板障组织呈低信号。第二名患者在T1加权序列上显示额叶低信号异常。该病变的颅内扩展与其他呈混合信号的佩吉特样骨的骨质溶解有关。第一名患者患有破骨细胞性佩吉特病或局限性骨质疏松。第二名患者发生了肉瘤样变性。
