Department of Anesthesiology, Division of Cardiothoracic Anesthesiology, Columbia University Medical Center, New York, NY, 10032, USA.
Department of Anesthesiology, Division of Cardiothoracic Anesthesiology, Cooper University Hospital, Camden, NJ, 08103, USA.
Best Pract Res Clin Anaesthesiol. 2017 Jun;31(2):261-272. doi: 10.1016/j.bpa.2017.04.004. Epub 2017 May 4.
Lung transplantation is a high-risk procedure that requires a highly trained cardiothoracic anesthesiologist and a considerable degree of vigilance. In the 50 years since the first lung transplantation, improvements in immunosuppression, preservation solutions, and surgical techniques and technologies have led to increased survival rates. The development of the extracorporeal circulatory membrane oxygenation allowed for bridge to transplantation and for donor organ recovery from primary graft dysfunction post transplantation [1]. In addition, changes in the criteria for lung allocation will cause the anesthesiologist to encounter older recipients with comorbidities that would have been disqualifying for transplantation a decade ago [2].
肺移植是一种高风险的手术，需要高度训练有素的心胸麻醉师和相当程度的警惕。自首例肺移植以来的 50 年中，免疫抑制、保存液、手术技术和技术的改进提高了存活率。体外循环膜氧合的发展使得可以进行移植桥接，并且可以从移植后原发性移植物功能障碍中恢复供体器官[1]。此外，肺分配标准的变化将导致麻醉师遇到十年前因合并症而不符合移植条件的老年受者[2]。
