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治疗伴有有限软组织侵犯的桡骨远端骨巨细胞瘤:刮除植骨术与广泛切除术的比较

Treatment of giant cell tumor of distal radius with limited soft tissue invasion: Curettage and cementing versus wide excision.

作者信息

Mozaffarian Kamran, Modjallal Mehra, Vosoughi Amir Reza

机构信息

Bone and Joint Diseases Research Center, Department of Orthopedic Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.

Department of Pathology, Dena Hospital, Shiraz, Iran.

出版信息

J Orthop Sci. 2018 Jan;23(1):174-179. doi: 10.1016/j.jos.2017.10.001. Epub 2017 Oct 27.

Abstract

BACKGROUND

Intralesional curettage and adjuvant versus wide en bloc excision (WEE) as the best treatment method of giant cell tumor (GCT) of distal radius with limited soft tissue extension is a controversial topic.

METHODS

Prospectively, 13 patients who had GCT of distal radius with perforation of either volar or dorsal cortex of the bone and soft tissue extension which was confined to one plane were enrolled in the study. Six patients treated with ICC and seven cases cured by WEE technique and proximal fibular arthroplasty. The results were evaluated based on recurrence, range of motion of the wrist joint, rotation of the forearm, grip and pinch power.

RESULTS

The mean age of the patients treated with ICC and WEE techniques were 32.7 (range: 23-43) and 34.5 (range: 28-44), respectively. Mean follow-up period was 72 months (range: 28-148). Local recurrence was seen in 4 of 6 patients (66.7%) underwent ICC technique but in none of the 7 subjects treated with WEE technique (P value = 0.021). The overall range of flexion/extension and supination/pronation in the WEE group were 83% and 92% of the ICC group, respectively. Both of pinch and grip power were 14% less in the WEE group compared to the ICC group.

CONCLUSIONS

In GCT lesion of distal radius even with limited soft tissue extension, WEE and proximal fibular arthroplasty may be a more reasonable suggestion when the patient seeks a one-shot surgery.

摘要

背景

对于软组织侵犯有限的桡骨远端骨巨细胞瘤,采用瘤内刮除术加辅助治疗与整块广泛切除术(WEE)作为最佳治疗方法是一个有争议的话题。

方法

前瞻性地纳入了13例桡骨远端骨巨细胞瘤患者,这些患者的掌侧或背侧皮质骨有穿孔且软组织侵犯局限于一个平面。6例患者接受了瘤内刮除术(ICC)治疗,7例患者通过WEE技术和近端腓骨置换术治愈。根据复发情况、腕关节活动范围、前臂旋转、握力和捏力对结果进行评估。

结果

接受ICC和WEE技术治疗的患者平均年龄分别为32.7岁(范围:23 - 43岁)和34.5岁(范围:28 - 44岁)。平均随访期为72个月(范围:28 - 148个月)。接受ICC技术治疗的6例患者中有4例(66.7%)出现局部复发,而接受WEE技术治疗的7例患者中无一例复发(P值 = 0.021)。WEE组的屈伸和旋前/旋后总体活动范围分别为ICC组的83%和92%。WEE组的捏力和握力均比ICC组低14%。

结论

对于桡骨远端骨巨细胞瘤,即使软组织侵犯有限,当患者寻求一次性手术时,WEE和近端腓骨置换术可能是更合理的建议。

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