漆树酸通过抑制组蛋白乙酰化减少人分化脂肪细胞中的脂肪生成。 - Suppr | 超能文献

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Anacardic acid reduces lipogenesis in human differentiated adipocytes via inhibition of histone acetylation.漆树酸通过抑制组蛋白乙酰化减少人分化脂肪细胞中的脂肪生成。

J Dermatol Sci. 2018 Jan;89(1):94-97. doi: 10.1016/j.jdermsci.2017.10.004. Epub 2017 Oct 18.

2

Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT.组蛋白乙酰转移酶（HAT）P300/CBP 抑制剂通过使 AKT 不稳定在 PTEN 缺陷的结直肠癌细胞中诱导合成致死性。

Int J Biol Sci. 2020 Mar 25;16(11):1774-1784. doi: 10.7150/ijbs.42197. eCollection 2020.

3

Anacardic acid ameliorates ultraviolet irradiation-induced damage to human skin.漆树酸可改善紫外线照射对人体皮肤造成的损伤。

J Dermatol Sci. 2017 Jun;86(3):252-255. doi: 10.1016/j.jdermsci.2017.03.019. Epub 2017 Mar 30.

4

Alcohol-induced histone H3K9 hyperacetylation and cardiac hypertrophy are reversed by a histone acetylases inhibitor anacardic acid in developing murine hearts.在发育中的小鼠心脏中，组蛋白乙酰化酶抑制剂漆树酸可逆转酒精诱导的组蛋白H3K9高乙酰化和心脏肥大。

Biochimie. 2015 Jun;113:1-9. doi: 10.1016/j.biochi.2015.03.012. Epub 2015 Mar 20.

5

Histone acetyltransferase p300 is induced by p38MAPK after photodynamic therapy: the therapeutic response is increased by the p300HAT inhibitor anacardic acid.光动力治疗后 p38MAPK 诱导组蛋白乙酰转移酶 p300：p300HAT 抑制剂芒果苷可增加治疗反应。

Free Radic Biol Med. 2015 Sep;86:118-32. doi: 10.1016/j.freeradbiomed.2015.05.009. Epub 2015 May 19.

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Critical role of histone acetylation by p300 in human placental 11β-HSD2 expression.p300 介导的组蛋白乙酰化在人胎盘 11β-HSD2 表达中的关键作用。

J Clin Endocrinol Metab. 2013 Jul;98(7):E1189-97. doi: 10.1210/jc.2012-4291. Epub 2013 May 28.

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Topical application of anacardic acid (6-nonadecyl salicylic acid) reduces UV-induced histone modification, MMP-13, MMP-9, COX-2 and TNF-α expressions in hairless mice skin.使用没食子酸（6-十九烷基水杨酸）进行局部涂抹可降低无毛小鼠皮肤中紫外线诱导的组蛋白修饰、基质金属蛋白酶-13（MMP-13）、基质金属蛋白酶-9（MMP-9）、环氧化酶-2（COX-2）和肿瘤坏死因子-α（TNF-α）的表达。

J Dermatol Sci. 2013 Apr;70(1):64-7. doi: 10.1016/j.jdermsci.2012.11.008. Epub 2012 Nov 23.

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Use of histone deacetylase inhibitors to examine the roles of bromodomain and histone acetylation in p300-dependent gene expression.使用组蛋白去乙酰化酶抑制剂来研究溴结构域和组蛋白乙酰化在p300依赖性基因表达中的作用。

Methods Mol Biol. 2013;977:353-7. doi: 10.1007/978-1-62703-284-1_28.

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Inhibition of PCAF by anacardic acid derivative leads to apoptosis and breaks resistance to DNA damage in BCR-ABL-expressing cells.漆树酸衍生物抑制 PCAF 导致表达 BCR-ABL 的细胞凋亡和破坏对 DNA 损伤的耐药性。

Anticancer Agents Med Chem. 2013 Jun;13(5):762-7. doi: 10.2174/1871520611313050010.

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Inhibition of DNA Methylation in the COL1A2 Promoter by Anacardic Acid Prevents UV-Induced Decrease of Type I Procollagen Expression.漆树酸对COL1A2启动子DNA甲基化的抑制作用可防止紫外线诱导的I型前胶原表达降低。

J Invest Dermatol. 2017 Jun;137(6):1343-1352. doi: 10.1016/j.jid.2017.02.005. Epub 2017 Feb 24.

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Histone Deacetylase 1 Reduces Lipogenesis by Suppressing SREBP1 Transcription in Human Sebocyte Cell Line SZ95.