Wiglusz Mariusz S, Landowski Jerzy, Michalak Lidia, Cubała Wiesław J
Department of Psychiatry, Medical University of Gdańsk, Poland.
Regional Epilepsy Outpatient Unit, Copernicus Hospital, Gdańsk, Poland.
Epilepsy Behav. 2017 Dec;77:58-61. doi: 10.1016/j.yebeh.2017.09.023. Epub 2017 Nov 5.
Despite the fact that depressive disorders are the most common comorbidities among patients with epilepsy (PWE), such disorders often go unrecognized and untreated. In addition, the availability of validated screening instruments to detect depression in PWE is limited. The aim of the present study was thus to validate the Polish version of the Beck Depression Inventory (BDI) in adult PWE.
A group of 118 outpatient PWE were invited to participate in the study. Ninety-six patients meeting the inclusion criteria completed the Polish Version of Beck Depression Inventory-I (BDI-I) and were examined by a trained psychiatrist using the Structured Clinical Interview (SICD-I) for Diagnostic and statistical manual of mental disorders - fourth edition (Text revision) (DSM-IV-TR). Receiver operating characteristic (ROC) curves were used to determine the optimal threshold scores for BDI.
Receiver operating characteristic analysis showed the area under the curve to be approximately 84%. For major depressive disorder (MDD) diagnosis, the BDI demonstrated the best psychometric properties for a cut-off score to be 18, with a sensitivity of 90.5%, specificity of 70.7%, positive predictive value (PPV) of 46.3%, and negative predictive value (NPV) of 96.4%. For the 'any depressive disorder' group, the BDI optimum cut-off score was 11, with a sensitivity of 82.5%, specificity of 73.2%, PPV of 68.8%, and NPV of 85.4%.
The BDI score is a valid psychometric indicator for depressive disorders in PWE maintaining adequate sensitivity and specificity, high NPV, and acceptable PPV with an optimum cut-off score of 18 for MDD diagnosis.
尽管抑郁症是癫痫患者(PWE)中最常见的共病,但此类疾病往往未被识别和治疗。此外,用于检测PWE抑郁症的有效筛查工具有限。因此,本研究的目的是验证成人PWE中贝克抑郁量表(BDI)的波兰语版本。
邀请118名门诊PWE患者参与研究。96名符合纳入标准的患者完成了波兰语版贝克抑郁量表-I(BDI-I),并由一名经过培训的精神科医生使用针对《精神疾病诊断与统计手册》第四版(文本修订版)(DSM-IV-TR)的结构化临床访谈(SICD-I)进行检查。采用受试者工作特征(ROC)曲线确定BDI的最佳阈值分数。
受试者工作特征分析显示曲线下面积约为84%。对于重度抑郁症(MDD)诊断,BDI显示出最佳心理测量特性的截断分数为18,敏感性为90.5%,特异性为70.7%,阳性预测值(PPV)为46.3%,阴性预测值(NPV)为96.4%。对于“任何抑郁症”组,BDI的最佳截断分数为11,敏感性为82.5%,特异性为73.2%,PPV为68.8%,NPV为85.4%。
BDI评分是PWE抑郁症的有效心理测量指标,具有足够的敏感性和特异性、高NPV以及可接受的PPV,MDD诊断的最佳截断分数为18。