Department of Psychiatry, Faculty of Medicine, Medical University of Gdańsk, Poland.
Department of Psychiatry, Faculty of Medicine, Medical University of Gdańsk, Poland.
Epilepsy Behav. 2019 Mar;92:221-225. doi: 10.1016/j.yebeh.2019.01.005. Epub 2019 Jan 25.
Anxiety disorders are frequent comorbid disorder in patients with epilepsy (PWEs). The availability of validated screening instruments to detect anxiety disorders in PWEs is limited. The aim of the present study was to validate State-Trait Anxiety Inventory (STAI) in adult PWEs for the detection of anxiety disorders.
A total of 96 outpatients with epilepsy completed the self-report symptom scale and were diagnosed with the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition Text Revision (DSM-IV-TR) Axis I disorders (SCID-I). The sensitivity, specificity, positive and negative predictive values, and receiver operating characteristic (ROC) curves were assessed to determine the optimal threshold scores for the State-Trait Anxiety Inventory State (STAI-S) and State-Trait Anxiety Inventory Trait (STAI-T) anxiety subscales.
Receiver operating characteristic analyses for STAI-T showed area under the curve at 84.7%. For diagnoses of anxiety disorders, the STAI-T demonstrated the best psychometric properties for a cutoff score ≥ 52 with sensitivity of 81.3%, specificity of 77.5%, positive predictive value (PPV) of 41.9%, and negative predictive value (NPV) of 95.4%.
The STAI-T proved to be a valid and reliable psychometric instrument in terms of screening for anxiety disorders in PWEs. In the epilepsy setting, STAI-T maintains adequate sensitivity, acceptable specificity, and high NPV but low PPV for diagnosing anxiety disorders with an optimum cutoff score ≥ 52.
焦虑症是癫痫患者（PWEs）常见的合并症。目前用于检测 PWEs 焦虑症的有效筛查工具有限。本研究旨在验证状态特质焦虑量表（STAI）在成年 PWEs 中用于检测焦虑症的有效性。
共有 96 名癫痫门诊患者完成了自我报告症状量表，并通过《精神障碍诊断与统计手册-第四版修订版》（DSM-IV-TR）轴 I 障碍结构性临床访谈（SCID-I）进行了诊断。评估了状态特质焦虑量表状态（STAI-S）和状态特质焦虑量表特质（STAI-T）焦虑分量表的敏感性、特异性、阳性和阴性预测值以及受试者工作特征（ROC）曲线，以确定最佳的 STAI-S 和 STAI-T 焦虑分量表的截断分数。
STAI-T 的 ROC 分析显示曲线下面积为 84.7%。对于焦虑症的诊断，STAI-T 在截断分数≥52 时具有最佳的心理测量特性，其敏感性为 81.3%，特异性为 77.5%，阳性预测值（PPV）为 41.9%，阴性预测值（NPV）为 95.4%。
STAI-T 被证明是一种有效的、可靠的心理测量工具，可用于筛查 PWEs 的焦虑症。在癫痫环境中，STAI-T 在诊断焦虑症时具有足够的敏感性、可接受的特异性和高的 NPV，但 PPV 较低，最佳截断分数≥52。
