Spadoto Mariângela, Sueitt Ana Paula Erbetta, Galinaro Carlos Alexandre, Pinto Tiago da Silva, Pompei Caroline Moço Erba, Botta Clarice Maria Rispoli, Vieira Eny Maria
a Water Resources and Applied Ecology Center, São Carlos School of Engineering, University of São Paulo , São Carlos , Brazil.
b Department of Hydraulics and Sanitation, São Carlos School of Engineering , University of São Paulo , São Carlos , Brazil.
Drug Chem Toxicol. 2018 Oct;41(4):449-458. doi: 10.1080/01480545.2017.1381109. Epub 2017 Nov 8.
Toxicities of bisphenol A (BPA) and nonylphenol (NP) to the neotropical freshwater cladocerans Ceriodaphnia silvestrii and Daphnia similis were studied under laboratory conditions. Acute exposures to BPA generated mean 48-h EC values of 14.44 (6.02-22.85) mg L for C. silvestrii and 12.05 (1.73-22.37) mg L for D. similis. When the organisms were exposed to acute doses of NP, mean 48-h EC values were 0.055 (0.047-0.064) mg L (C. silvestrii) and 0.133 (0.067-0.200) mg L (D. similis). Ceriodaphnia silvestrii was also tested in chronic bioassays, which resulted in mean 8-d IC values of 2.43 (2.16-2.69) mg L BPA [no observed effect concentration (NOEC): 1.38 mg L] and 0.020 (0.015-0.026) mg L NP (NOEC: 0.015 mg L). These laboratory tests are valuable to broaden the understanding of the environmental threat posed by BPA and NP in aquatic ecosystems, and to increase the knowledge about the sensitivity of neotropical indigenous species to these contaminants. In addition to the laboratory bioassays, species sensitivity distributions were used to suggest protective concentrations of BPA and NP to prevent adverse effects on freshwater organisms. According to the obtained results, concentrations lower than 36.47 µg L BPA and 1.39 µg L NP are not expected to adversely impact aquatic organisms in natural ecosystems.
在实验室条件下，研究了双酚A（BPA）和壬基酚（NP）对新热带淡水枝角类动物西尔维斯特仙达溞和相似水蚤的毒性。BPA急性暴露对西尔维斯特仙达溞产生的48小时平均半数效应浓度（EC）值为14.44（6.02 - 22.85）mg/L，对相似水蚤为12.05（1.73 - 22.37）mg/L。当生物体暴露于急性剂量的NP时，48小时平均EC值分别为0.055（0.047 - 0.064）mg/L（西尔维斯特仙达溞）和0.133（0.067 - 0.200）mg/L（相似水蚤）。还对西尔维斯特仙达溞进行了慢性生物测定，结果显示BPA的8天平均半数抑制浓度（IC）值为2.43（2.16 - 2.69）mg/L [无观察到效应浓度（NOEC）：1.38 mg/L]，NP的为0.020（0.015 - 0.026）mg/L（NOEC：0.015 mg/L）。这些实验室测试对于拓宽对BPA和NP对水生生态系统造成的环境威胁的理解，以及增加关于新热带本土物种对这些污染物敏感性的知识很有价值。除了实验室生物测定外，还使用物种敏感性分布来建议BPA和NP的保护浓度，以防止对淡水生物产生不利影响。根据所得结果，预计低于36.47 μg/L BPA和1.39 μg/L NP的浓度不会对自然生态系统中的水生生物产生不利影响。
