Pal Bikramjit P, Garge Saili, Khetan Vikas
Department of Vitreoretina, Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Oman J Ophthalmol. 2017 Sep-Dec;10(3):135-144. doi: 10.4103/ojo.OJO_234_2016.
Choroidal melanoma (CM), the most common intraocular tumor in adults, is still a rarity in Asia. Having a high propensity for metastasis with a poor survival, recognizing it early is essential. Although it has typical clinical features, there are instances of simulating lesions. Fine-needle aspiration biopsy can be a valuable tool not only to confirm our clinical suspicion but also aid in prognosticating it. From days of histopathological prognostic markers, we are moving on to genetic markers which are reliably providing insights, helping us in providing a better care for our patients. Eye preservation has taken an all new important meaning in CM with many centers opting for different modalities of radiation. Herein, we try to provide a short synopsis of CM looking into its epidemiology, clinical features, diagnosis, and management. We also look briefly into the role of fine-needle biopsy in managing CM. Being a tertiary referral ocular center in India, we do come across CM; we have shared the preliminary reports of our analysis of managing CM over a 9-year period.
脉络膜黑色素瘤(CM)是成人最常见的眼内肿瘤,但在亚洲仍较为罕见。其转移倾向高,生存率低,早期识别至关重要。尽管它有典型的临床特征,但也存在类似病变的情况。细针穿刺活检不仅是确认临床怀疑的有价值工具,还有助于对其进行预后评估。从组织病理学预后标志物时代,我们正迈向能可靠提供见解的基因标志物,这有助于我们为患者提供更好的护理。在CM中,保眼具有全新的重要意义,许多中心选择不同的放疗方式。在此,我们试图简要概述CM,包括其流行病学、临床特征、诊断和管理。我们还简要探讨细针活检在CM管理中的作用。作为印度的三级转诊眼科中心,我们确实遇到过CM;我们分享了9年来CM管理分析的初步报告。