Silverberg Nanette B
Department of Dermatology, Mt Sinai West of the Icahn School of Medicine, New York, New York, USA.
Cutis. 2017 Sep;100(3):173;177;192.
Atopic dermatitis (AD) is the cause of substantial morbidity including severe pruritus and impaired personal and familial quality of life. Furthermore, the rising incidence and familial association of AD have highlighted the need for disease prevention. It is largely genetic in nature and cannot be avoided in all cases. However, low-risk prevention strategies have been attempted to reduce triggering of first onset of AD in predisposed individuals. Therapeutics for active disease include trigger avoidance, barrier repair, topical medicaments including topical corticosteroids (TCs) and nonsteroidal agents, phototherapy, and antibacterial interventions.
特应性皮炎(AD)会导致包括严重瘙痒以及个人和家庭生活质量受损在内的大量发病情况。此外,AD发病率的上升及其家族关联性凸显了疾病预防的必要性。AD在很大程度上具有遗传性质,在所有情况下都无法避免。然而,人们已尝试采用低风险预防策略来减少易感个体首次发作AD的触发因素。活动性疾病的治疗方法包括避免触发因素、屏障修复、外用药物(包括外用糖皮质激素(TCs)和非甾体类药物)、光疗以及抗菌干预措施。