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胃淋巴细胞性静脉炎病例报告,一种罕见的恶性肿瘤模仿症。

A case report of gastric lymphocytic phlebitis, a rare mimic for malignancy.

作者信息

Chan Daniel L, Ravindran Praveen, Chua Dorothy, Smith Jason D, Wong King S, Ghusn Michael A

机构信息

Department of Surgery, The Tweed Hospital, Tweed Heads, NSW, Australia; Faculty of Medicine, University of New South Wales, NSW, Australia.

Department of Surgery, The Tweed Hospital, Tweed Heads, NSW, Australia.

出版信息

Int J Surg Case Rep. 2017;41:269-271. doi: 10.1016/j.ijscr.2017.10.047. Epub 2017 Nov 2.

Abstract

INTRODUCTION

Lymphocytic phlebitis is a benign condition characterised by inflammation of the veins and rarely affects the gastrointestinal tract. Reported cases present as acute abdomen and involve the colon or small intestine. We report the fourth case of gastric lymphocytic phlebitis in the literature.

PRESENTATION OF CASE

A 74-year-old female presented with eight weeks of abdominal pain. Findings at endoscopy were suggestive of a malignant ulcer on the greater curvature of antrum, while biopsies showed chronic gastritis without malignancy. Appearance at diagnostic laparoscopy was consistent with a malignant gastric ulcer with serosal changes. Due to persistent pain and the macroscopic appearance, she proceeded to have an open subtotal gastrectomy and D2 lymph node clearance. Despite macroscopic appearance, the microscopic examination demonstrated no malignancy, and was consistent with lymphocytic phlebitis with overlying ulceration.

DISCUSSION

This case was a mimic for gastric malignancy, with the benign diagnosis only being made after surgical resection. Gastric lymphocytic phlebitis is a rare differential diagnosis for gastric ulcers when biopsies are negative, although preoperative diagnosis is difficult given the lesions do not involve the mucosa.

CONCLUSION

If clinical history and endoscopic findings are suspicious for malignancy, despite normal biopsies, an aggressive surgical resection remains reasonable given the rarity gastric lymphocytic phlebitis.

摘要

引言

淋巴细胞性静脉炎是一种以静脉炎症为特征的良性疾病,很少累及胃肠道。报道的病例表现为急腹症,累及结肠或小肠。我们报告了文献中第四例胃淋巴细胞性静脉炎。

病例介绍

一名74岁女性出现腹痛8周。内镜检查结果提示胃窦大弯处有恶性溃疡,而活检显示为慢性胃炎,无恶性病变。诊断性腹腔镜检查的外观与伴有浆膜改变的恶性胃溃疡一致。由于持续疼痛和宏观表现,她接受了开放性胃大部切除术和D2淋巴结清扫术。尽管宏观表现如此,但显微镜检查未发现恶性病变,符合伴有溃疡形成的淋巴细胞性静脉炎。

讨论

该病例酷似胃恶性肿瘤,仅在手术切除后才做出良性诊断。当活检为阴性时,胃淋巴细胞性静脉炎是胃溃疡的一种罕见鉴别诊断,尽管鉴于病变未累及黏膜,术前诊断困难。

结论

如果临床病史和内镜检查结果怀疑为恶性肿瘤,尽管活检正常,但鉴于胃淋巴细胞性静脉炎罕见,积极的手术切除仍是合理的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/801f/5681333/7ecc3bd9497a/gr1.jpg

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