Kishaba Tomoo
Department of Respiratory Medicine, Okinawa Chubu Hospital, Okinawa, Japan.
Eurasian J Med. 2017 Oct;49(3):204-206. doi: 10.5152/eurasianjmed.2017.17219.
Idiopathic pulmonary fibrosis (IPF) is the most common cause of chronic diffuse parenchymal disease of unknown cause. However, IPF patients sometimes develop acute exacerbation (AE), which is a life-threatening condition. The cause of AE of IPF remains unknown. The new criteria for AE of IPF have been proposed last year, wherein both idiopathic and triggered AE were proposed. Triggered AE includes infection, post-procedure and post-operation, drug toxicity, and aspiration. Therefore, detailed history taking is crucial. In this review, the definition, clinical symptoms, chest imaging, management, and prognosis for AE of IPF are described.
特发性肺纤维化（IPF）是原因不明的慢性弥漫性实质性疾病的最常见病因。然而，IPF患者有时会发生急性加重（AE），这是一种危及生命的情况。IPF急性加重的病因尚不清楚。去年提出了IPF急性加重的新标准，其中包括特发性和诱发型AE。诱发型AE包括感染、操作后和手术后、药物毒性及误吸。因此，详细的病史采集至关重要。在本综述中，描述了IPF急性加重的定义、临床症状、胸部影像学、管理及预后。
