Dyrla Przemysław, Gil Jerzy, Niemczyk Stanisław, Saracyn Marek, Kosik Krzysztof, Czarkowski Sebastian, Lubas Arkadiusz
Department of Gastroenterology, Military Institute of Medicine, Warsaw Poland.
Department of Internal Medicine, Nephrology and Dialysis, Military Institute of Medicine, Warsaw, Poland.
Prz Gastroenterol. 2017;12(3):192-198. doi: 10.5114/pg.2017.70472. Epub 2017 Sep 30.
The growing incidence of gastrointestinal diseases forces to improve both imaging techniques and the identification of the population with a greater risk of a disease. Identification of lesions located inside the wall of intestinal tract or in close proximity often was not possible using endoscopy or computed tomography.
The study was a retrospective evaluation of the occurrence of submucosal lesions (SML) and thickened wall (TW) of the upper gastrointestinal tract (UGIT) depending on age and sex.
Out of 20012 gastroscopies during the 4-year follow-up study, we enrolled 199 patients with pathological lesions in the wall of the UGIT. All patients underwent computed tomography and endoscopic ultrasound (EUS).
We analysed a total of 122 (78 males, 44 females, age: 64.0 ±12.9 years) out of 187 patients. 23.91% of SML in the oesophagus, 56.52% in the stomach, and 19.57% in the duodenum. A higher number of SMLs was found in men than in women (57.14% vs. 40.45%, = 0.023), and the difference was greater over 50 years of age (85.71% vs. 40.00%, = 0.031). We found less malignant SMLs compared to benign (35.87% vs. 64.13%, = 0.026), especially in women (22.86% vs. 47.46%, = 0.006). 26.67% of TW were in the oesophagus, 66.67% in the stomach, and 6.67% in the duodenum. There was a tendency towards increased incidence of TW over 50 years of age (8.58% vs. 18.30%, = 0.074), which concerned men in particular (24.10% vs. 11.43%, = 0.043). Until 65 years of age, these differences were significant for the oesophagus (27.27% vs. 0.00%, = 0.044) and the stomach (25.93% vs. 4.00%, = 0.029). As many as 70% of TW pathologies were malignant.
Submucosal lesions and TW of the upper gastrointestinal tract account for 0.61% of performed gastroscopies. They occur in men and usually over 50 years of age.
胃肠道疾病发病率的不断上升促使成像技术以及对疾病高风险人群的识别都得到改进。使用内窥镜检查或计算机断层扫描往往无法识别位于肠道壁内或紧邻肠道壁的病变。
本研究是一项回顾性评估，旨在根据年龄和性别分析上消化道（UGIT）黏膜下病变（SML）和肠壁增厚（TW）的发生率。
在为期4年的随访研究中的20012例胃镜检查中，我们纳入了199例上消化道壁有病理病变的患者。所有患者均接受了计算机断层扫描和内镜超声检查（EUS）。
我们分析了187例患者中的122例（男性78例，女性44例，年龄：64.0±12.9岁）。食管SML占23.91%，胃占56.52%，十二指肠占19.57%。男性发现的SML数量多于女性（57.14%对40.45%，P = 0.023），50岁以上差异更大（85.71%对40.00%，P = 0.031）。与良性SML相比，我们发现恶性SML较少（35.87%对64.13%，P = 0.026），尤其是女性（22.86%对47.46%，P = 0.006）。TW中26.67%位于食管，66.67%位于胃，6.67%位于十二指肠。50岁以上TW的发生率有上升趋势（8.58%对18.30%，P = 0.074），这在男性中尤为明显（24.10%对11.43%，P = 0.043）。在65岁之前，食管（27.27%对0.00%，P = 0.044）和胃（25.93%对4.00%，P = 0.029）的这些差异具有统计学意义。多达70%的TW病变为恶性。
上消化道的黏膜下病变和TW占所施行胃镜检查的0.61%。它们多见于男性，且通常发生在50岁以上人群。
