小剂量地高辛、维拉帕米和普萘洛尔导致甲状腺功能亢进诱发的心房扑动-颤动并伴有严重的窦房结停搏。
Hyperthyroid-induced atrial flutter-fibrillation with profound sinoatrial nodal pauses due to small doses of digoxin, verapamil, and propranolol.
作者信息
Talley J D, Wathen M S, Hurst J W
机构信息
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
出版信息
Clin Cardiol. 1989 Jan;12(1):45-7. doi: 10.1002/clc.4960120109.
Atrial fibrillation due to hyperthyroidism is characterized by a rapid ventricular response which is typically resistant to digoxin therapy. We report a patient with atrial flutter-fibrillation who developed cyclic sinus node dysfunction with profound ventricular pauses in response to small doses of digoxin, verapamil, and propranolol, which resolved with discontinuation of the medications. Caution is necessary to avoid paradoxical ventricular slowing when treating hyperthyroid-induced atrial fibrillation.
甲状腺功能亢进所致心房颤动的特点是心室反应迅速，通常对洋地黄治疗耐药。我们报告1例心房扑动-颤动患者，其在使用小剂量洋地黄、维拉帕米和普萘洛尔后出现周期性窦房结功能障碍并伴有严重心室停搏，停药后症状缓解。治疗甲状腺功能亢进所致心房颤动时，必须注意避免出现矛盾性心室率减慢。
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