口腔潜在恶性疾病的评估与管理
Evaluation and Management of Oral Potentially Malignant Disorders.
作者信息
Nadeau Christine, Kerr Alexander Ross
机构信息
Faculty of Dentistry, Université Laval, Pavillon de Médecine dentaire, 2420 rue de la Terasse, Québec, Québec G1V 0A6, Canada.
Department of Oral and Maxillofacial Pathology, Radiology and Medicine, NYU College of Dentistry, 345 East 24th Street, New York, NY 10010, USA.
出版信息
Dent Clin North Am. 2018 Jan;62(1):1-27. doi: 10.1016/j.cden.2017.08.001. Epub 2017 Oct 18.
Oral potentially malignant disorders (OPMDs) refer to epithelial lesions and conditions with an increased risk for malignant transformation; oral leukoplakia is the most commonly encountered. Overall, OPMDs have a low risk for malignant transformation, yet the challenge is the difficulty to reliably identify and predict which patients with OPMDs are at the highest risk for malignant transformation. Future research is needed to elucidate the molecular aspects of OPMDs, to improve current diagnostic strategies, leading to personalized management.
口腔潜在恶性疾病（OPMDs）是指上皮性病变及具有恶变风险增加的情况；口腔白斑是最常见的一种。总体而言，OPMDs恶变风险较低，但面临的挑战是难以可靠地识别和预测哪些OPMDs患者具有最高的恶变风险。需要开展进一步研究以阐明OPMDs的分子层面情况，改进当前的诊断策略，从而实现个性化管理。
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