Zhang Chundong, Wang Xin, Tang Jie
Department of Ultrasound, PLA Bethune International Peace Hospital, No. 398, Zhongshanxi Road, Shijiazhuang, 050081, People's Republic of China.
Department of Pediatrics, PLA Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
J Med Ultrason (2001). 2018 Apr;45(2):307-313. doi: 10.1007/s10396-017-0841-2. Epub 2017 Nov 10.
To explore the microcirculation formation mechanism of contrast-enhanced (CE) ultrasonography imaging performance in rabbits with limb muscle crush injury.
Seventy-two New Zealand white rabbits were randomly divided into two groups. A limb muscle crush injury model was created by airing a balloon cuff device with a force of 40 kpa. CE ultrasonography parameters were detected in the first group. In vivo microcirculation parameters were detected in the second group. Fine blood vessel diameter and blood flow velocity were calculated before extrusion and 0.5, 2, 6, 24 h, and 3 days after decompression.
Compared with the uninjured muscle, reperfusion of the injured muscles showed early and high enhancement in CE ultrasonography images. The time-intensity curve showed a trend of rapid elevation and gradual drop. Compared with the control group, fine artery and vein diameters in the experimental group were wider and the blood flow velocity was slower, especially in the fine veins.
In vivo microcirculation detection can reflect changes in muscle microvascular diameter and blood flow velocity, which have a correlation with quantitative ultrasound imaging parameters.
探讨肢体肌肉挤压伤家兔对比增强（CE）超声成像性能的微循环形成机制。
将72只新西兰白兔随机分为两组。通过用40 kpa的力充气气球袖带装置建立肢体肌肉挤压伤模型。第一组检测CE超声参数。第二组检测体内微循环参数。计算挤压前及减压后0.5、2、6、24小时和3天的微血管直径和血流速度。
与未损伤肌肉相比，损伤肌肉的再灌注在CE超声图像中显示出早期和高度增强。时间-强度曲线呈快速升高和逐渐下降的趋势。与对照组相比，实验组的微动脉和微静脉直径更宽，血流速度更慢，尤其是在微静脉中。
体内微循环检测可反映肌肉微血管直径和血流速度的变化，这些变化与定量超声成像参数相关。
