Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Clin Chest Med. 2017 Dec;38(4):741-749. doi: 10.1016/j.ccm.2017.07.014. Epub 2017 Sep 21.
Despite significant advances in surgical techniques, perioperative care, and immunosuppressive therapy, solid organ transplantation still carries considerable risk of complications. Pulmonary complications, in particular, are a major cause of morbidity and mortality. Although infectious complications prevail, the lungs are also vulnerable to a variety of noninfectious complications related to the transplant surgery and adverse effects of the immunosuppressive regimen. This article focuses on noninfectious pulmonary complications associated with the 3 most commonly performed solid organ transplant procedures: liver, kidney, and heart.
尽管手术技术、围手术期护理和免疫抑制治疗取得了重大进展,但实体器官移植仍然存在相当大的并发症风险。肺部并发症尤其成为发病率和死亡率的主要原因。虽然感染性并发症占主导地位,但肺部也容易受到与移植手术和免疫抑制方案的不良反应相关的各种非感染性并发症的影响。本文重点介绍与 3 种最常进行的实体器官移植手术(肝、肾和心脏)相关的非感染性肺部并发症。