Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, 17 East 102nd Street, 2nd Floor, New York, NY 10029, USA.
Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, 17 East 102nd Street, 2nd Floor, New York, NY 10029, USA.
Clin Liver Dis. 2018 Feb;22(1):213-227. doi: 10.1016/j.cld.2017.08.015. Epub 2017 Oct 6.
The number of transplants caused by nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NASH) has been progressively increasing and this is expected to become the most common indication for liver transplant in the United States. Patients with NASH show many features of the metabolic syndrome and, as a result, are at higher risk for postoperative cardiovascular morbidity and mortality. Despite this, patients with NASH have long-term graft and patient survival rates comparable with other causes of chronic liver disease. Posttransplant metabolic syndrome is a common occurrence that increases the risk of steatosis in the graft liver.
非酒精性脂肪性肝病/非酒精性脂肪性肝炎（NASH）导致的移植数量一直在逐渐增加，预计这将成为美国最常见的肝移植适应证。NASH 患者表现出多种代谢综合征的特征，因此术后发生心血管发病率和死亡率的风险更高。尽管如此，NASH 患者的长期移植物和患者存活率与其他慢性肝病的原因相当。移植后代谢综合征是一种常见的情况，会增加移植肝脂肪变性的风险。
