Myers M M, Brunelli S A, Squire J M, Shindeldecker R D, Hofer M A
Department of Developmental Psychobiology, NYS Psychiatric Institute, NY 10032.
Dev Psychobiol. 1989 Jan;22(1):29-53. doi: 10.1002/dev.420220104.
In Part I of this study maternal behavior of 15 spontaneously hypertensive (SHR) and 11 Wistar-Kyoto (WKY) rat mothers was recorded throughout the preweaning period. SHR mothers were observed: 1) in arched-and blanket-nursing postures more often, and in passive-nursing posture less often, 2) licking their pups more often, and 3) resting less often. Further, SHR mothers retrieved their pups more quickly than did WKY. In the second part of this study we found that a composite maternal behavior score, derived from summing occurrences of mother/pup contact, arched-nursing, and pup-licking, was positively correlated with the offspring blood pressures. This relationship, which accounted for 43.5% of the variance in adult blood pressure, suggests that certain types of interactions between mothers and their pups may contribute to individual differences in cardiovascular system development.
在本研究的第一部分，记录了15只自发性高血压（SHR）大鼠母亲和11只Wistar-Kyoto（WKY）大鼠母亲在断奶前整个时期的母性行为。观察到SHR母亲：1）更频繁地采用拱背和裹腹哺乳姿势，而较少采用被动哺乳姿势；2）更频繁地舔舐幼崽；3）休息较少。此外，SHR母亲找回幼崽的速度比WKY母亲更快。在本研究的第二部分，我们发现，通过对母婴接触、拱背哺乳和舔舐幼崽的次数进行汇总得出的综合母性行为评分与后代血压呈正相关。这种关系解释了成年血压变异的43.5%，表明母亲与幼崽之间的某些互动类型可能导致心血管系统发育的个体差异。
