Surgical Outcomes and Quality Improvement Center, Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Division of Vascular Surgery, Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Am J Surg. 2018 Jul;216(1):25-30. doi: 10.1016/j.amjsurg.2017.10.035. Epub 2017 Nov 1.
Surgeons play a pivotal role in the opioid epidemic but it is unknown how different members of a surgical team vary in the way they prescribe opioids after surgical episodes.
We conducted a retrospective cohort study of all inpatient discharges for 5 common surgeries. Total number of tablets and total milligram equivalents (MME) prescribed were calculated and differences in prescription patterns were determined for attending surgeons, surgical residents and advanced practice providers. Using a generalized ordered logistic regression, we examined factors associated with ordering a higher number of tablets or MME.
The median number of tablets (range) prescribed by rank were attending surgeon 30 (6-72), surgical resident 20 (6-189) and advanced care practitioner 40 (5-1000); p < 0.001.The median total MME prescribed by rank were attending surgeon 140 (30-600), surgical resident 200 (30-1600) and advanced practice provider 240 (25-1000); p < 0.001. There was no statistically significant difference by resident postgraduate year (PGY) for both total tablets and total MME prescribed. General surgery residents on average ordered a narrower range of total MME compared to surgical residents in other surgical specialties [20 (50-600) vs 20 (30-1600); p = 0.03]. On regression analysis, residents were less likely to order a higher number of tablets compared to attending surgeons (OR 0.29, p = 0.01). However, surgical residents and advanced care providers were more likely to prescribe a higher total MME compared to attending surgeons (OR 7.12, p < 0.001; OR 3.39, p = 0.01 for surgical resident and OR 6.46, p = 0.01) for advanced practice providers).
There is wide variation in opioid prescription patterns by surgical providers. More studies are needed to clearly define the ideal number of tablets or MMEs to prescribe for common surgical procedures.
外科医生在阿片类药物流行中起着关键作用,但尚不清楚手术团队的不同成员在手术后开具阿片类药物的方式上有何不同。
我们对 5 种常见手术的所有住院患者进行了回顾性队列研究。计算了开具的片剂总数和总毫克当量 (MME),并确定了主治外科医生、外科住院医师和高级执业医师的处方模式差异。使用广义有序逻辑回归,我们研究了与开具更多片剂或 MME 相关的因素。
按职级开处方的片剂中位数(范围)分别为主治外科医生 30 片(6-72 片)、外科住院医师 20 片(6-189 片)和高级护理医生 40 片(5-1000 片);p<0.001。按职级开具的总 MME 中位数分别为主治外科医生 140 MME(30-600 MME)、外科住院医师 200 MME(30-1600 MME)和高级护理医生 240 MME(25-1000 MME);p<0.001。无论是总片剂还是总 MME,住院医师的研究生后年份(PGY)均无统计学差异。与其他外科专业的外科住院医师相比,普通外科住院医师平均开具的总 MME 范围较窄[20 MME(50-600 MME)与 20 MME(30-1600 MME);p=0.03]。在回归分析中,与主治外科医生相比,住院医师开出的片剂数量较少的可能性较小(比值比 0.29,p=0.01)。然而,与主治外科医生相比,外科住院医师和高级护理医生开具更高总 MME 的可能性更大(比值比 7.12,p<0.001;外科住院医师的比值比 3.39,p=0.01;高级护理医生的比值比 6.46,p=0.01))。
外科医生开具阿片类药物的处方模式存在很大差异。需要进一步研究来明确规定常见手术的理想片剂或 MME 数量。