Markowitz Jonathan E, Clayton Steven B
Pediatric Gastroenterology and Nutrition, Children's Hospital of Greenville Health System, University of South Carolina School of Medicine-Greenville, 200 Patewood Drive, Suite A-140, Greenville, SC 29615, USA.
Gastroenterology and Liver Center, Greenville Health System, University of South Carolina School of Medicine-Greenville, 890 West Faris Road, Suite 100, Greenville, SC 29605, USA.
Gastrointest Endosc Clin N Am. 2018 Jan;28(1):59-75. doi: 10.1016/j.giec.2017.07.004.
Adults and children with eosinophilic esophagitis (EoE) have distinct clinical and endoscopic presentations. Recognition of clinical signs, along with laboratory and endoscopic findings, is critical for the identification of patients with EoE because delay in diagnosis has been associated with esophageal remodeling and stricture formation. Clinical presentation varies considerably between adults and children. This is less due to differences in the disease and more due to patient differences. This article describes the similarities and differences in clinical presentation of children and adults with EoE, including areas of epidemiology, clinical and endoscopic presentation, pathophysiology, and treatment.
嗜酸性食管炎（EoE）的成人和儿童患者具有不同的临床和内镜表现。认识临床体征以及实验室和内镜检查结果，对于识别EoE患者至关重要，因为诊断延迟与食管重塑和狭窄形成有关。成人和儿童的临床表现差异很大。这与其说是疾病本身的差异，不如说是患者个体的差异。本文描述了EoE成人和儿童患者临床表现的异同，包括流行病学、临床和内镜表现、病理生理学及治疗等方面。
