Toronto Rehabilitation Institute, University Center, 550 University Ave, Toronto, ON M5G 2A2, Canada; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Toronto, Toronto, ON, Canada.
PM R. 2018 Jun;10(6):623-635. doi: 10.1016/j.pmrj.2017.10.013. Epub 2017 Nov 10.
Current evidence suggests that corticosteroid injection alone expedites the recovery of pain-free range of motion (ROM) in patients with adhesive capsulitis compared to physiotherapy or placebo. However, it remains unclear whether the addition of hydrodilatation with corticosteroid provides improvement in pain-free ROM as well as pain relief.
A review of the literature was conducted to determine whether the combined intervention of hydrodilatation and corticosteroid injection expedites restoration of pain-free ROM compared to a control treatment of corticosteroid injection in patients with adhesive capsulitis.
EMBASE, MEDLINE, and CINAHL were searched from database inception to January 2017. Relevant studies were determined as randomized controlled trials written in English, comparing the outcomes of hydrodilatation and corticosteroid injection to a control group treated with corticosteroid injection alone in patients with adhesive capsulitis. Two independent reviewers assessed manuscripts for study inclusion and extracted data.
A total of 2276 studies were identified through the search, of which 6 randomized controlled studies (involving 410 shoulders) met criteria for inclusion in this review. Mean age ranged from 51-61 years, with mean symptom duration of 4-9 months. Studies varied significantly regarding the volume of injectate, anatomical injection approach, symptom duration, and the method of glenohumeral capsule distension (capsular rupture versus preservation). Two studies demonstrated clinically and statistically significant improvement in the combination group at 3-month follow-up, and one study demonstrated clinically significant improvement only in ROM and/or pain/functional scales, compared to 3 studies demonstrating no benefit when compared to corticosteroid injection alone.
Combining hydrodilatation with corticosteroid injection potentially expedites recovery of pain-free ROM. The greatest benefit is experienced within the first 3 months of intervention. Differences in hydrodilatation techniques, inclusion of capsular preservation, anatomical approach, and length of symptoms may explain the variability in efficacy demonstrated. Further trials using larger sample sizes, better anatomical approaches, image guidance, and hydrodilatation techniques are required to determine the true nature of benefits of hydrodilatation with corticosteroid injection.
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目前的证据表明,与物理治疗或安慰剂相比,单独使用皮质类固醇注射可以加速粘连性囊炎患者无痛活动范围(ROM)的恢复。然而,皮质类固醇注射联合水扩张治疗是否能改善无痛 ROM 和疼痛缓解,目前仍不清楚。
对文献进行综述,以确定与单独使用皮质类固醇注射的对照组相比,水扩张联合皮质类固醇注射的联合干预是否能加速粘连性囊炎患者无痛 ROM 的恢复。
从数据库建立开始到 2017 年 1 月,对 EMBASE、MEDLINE 和 CINAHL 进行了检索。将以英语撰写的、比较水扩张和皮质类固醇注射与单独使用皮质类固醇注射治疗粘连性囊炎患者的对照组的结果的随机对照试验确定为相关研究。两名独立的评审员评估手稿以确定其是否符合纳入标准,并提取数据。
通过检索共确定了 2276 项研究,其中 6 项随机对照研究(涉及 410 个肩部)符合纳入本综述的标准。平均年龄为 51-61 岁,平均症状持续时间为 4-9 个月。研究在注射量、解剖注射方法、症状持续时间和肱骨头关节囊扩张方法(囊破裂与保留)方面存在显著差异。两项研究在 3 个月随访时显示联合组在临床和统计学上有显著改善,一项研究仅在 ROM 和/或疼痛/功能量表上显示出显著改善,而三项研究显示与单独使用皮质类固醇注射相比没有益处。
将水扩张与皮质类固醇注射相结合可能会加速无痛 ROM 的恢复。干预后的前 3 个月效果最大。水扩张技术、囊保留、解剖方法和症状持续时间的差异可能解释了疗效的差异。需要进一步进行更大样本量、更好的解剖方法、影像学引导和水扩张技术的试验,以确定皮质类固醇注射联合水扩张的真正益处。
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