Kou W H, Morady F, Dick M, Nelson S D, Baerman J M
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor.
J Am Coll Cardiol. 1989 Feb;13(2):391-8. doi: 10.1016/0735-1097(89)90517-2.
The purpose of this study was to determine whether concealed anterograde accessory pathway conduction occurs during the induction of orthodromic tachycardia by an atrial extrastimulus (S2). Sixteen patients with an overt (n = 9) or concealed (n = 7) accessory pathway had inducible orthodromic tachycardia by S2 during an atrial drive (S1) cycle length of 500 to 650 ms. A ventricular extrastimulus (S3) was introduced coincident with the His depolarization resulting from S2 during the longest S1S2 interval that reproducibly induced orthodromic tachycardia. The S1S3 interval was decreased in 10 ms steps until S3 reached ventricular refractoriness. Retrograde accessory pathway conduction of S3 in the presence and absence of S2 was compared at the same S1S3 intervals. In the absence of S2 there was retrograde accessory pathway conduction after S3 in each patient. In the presence of S2, in patients with overt pre-excitation, retrograde accessory pathway conduction after S3 was absent in one patient, prolonged in four patients and present only after long S1S3 intervals in three patients. Only one patient had unchanged retrograde conduction regardless of the presence or absence of S2. In patients with a concealed accessory pathway, retrograde accessory pathway conduction after S3 was absent in five patients and was prolonged in two. Thus, concealed anterograde accessory pathway conduction was present in 15 of 16 patients at the time of orthodromic tachycardia induction. In conclusion, concealed anterograde accessory pathway conduction occurs in a majority of patients with an overt or a concealed accessory pathway during induction of orthodromic tachycardia by an atrial extrastimulus.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是确定在心房期外刺激(S2)诱发顺向型心动过速期间是否发生隐匿性前传旁路传导。16例有显性(n = 9)或隐匿性(n = 7)旁路的患者,在心房驱动(S1)周期长度为500至650毫秒时,可被S2诱发顺向型心动过速。在可重复诱发顺向型心动过速的最长S1S2间期期间,引入与S2导致的希氏束去极化同时发生的心室期外刺激(S3)。S1S3间期以10毫秒的步长缩短,直至S3达到心室不应期。在相同的S1S3间期比较有和没有S2时S3的逆向旁路传导。没有S2时,每位患者S3后均有逆向旁路传导。有S2时,在有显性预激的患者中,1例患者S3后无逆向旁路传导,4例患者延长,3例患者仅在长S1S3间期后出现。只有1例患者无论有无S2,逆向传导均无变化。在有隐匿性旁路的患者中,5例患者S3后无逆向旁路传导,2例患者延长。因此,在16例患者中有15例在诱发顺向型心动过速时存在隐匿性前传旁路传导。总之,在心房期外刺激诱发顺向型心动过速期间,大多数有显性或隐匿性旁路的患者会发生隐匿性前传旁路传导。(摘要截断于250字)