钙通道速成课程。
A Crash Course in Calcium Channels.
作者信息
Zamponi Gerald W
机构信息
Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary , Calgary T2N 1N4, Canada.
出版信息
ACS Chem Neurosci. 2017 Dec 20;8(12):2583-2585. doi: 10.1021/acschemneuro.7b00415. Epub 2017 Nov 13.
Much progress has been made in understanding the molecular physiology and pharmacology of calcium channels. Recently, there have been tremendous advances in learning about calcium channel structure and function through crystallography and cryo-electron microscopy studies. Here, I will give an overview of our knowledge about calcium channels, and highlight two recent studies that give important insights into calcium channel structure.
在理解钙通道的分子生理学和药理学方面已经取得了很大进展。最近，通过晶体学和冷冻电子显微镜研究，在了解钙通道的结构和功能方面取得了巨大进展。在此，我将概述我们对钙通道的认识，并重点介绍两项最近的研究，它们为钙通道结构提供了重要见解。
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