Wang Li-Ping, Chen Shou-Ping, Huang Yu-Ying, Qin Fang-Fang, Ou Wen, Liu Hong-Dong, Deng Xiao-Fang, Lou Lei, Tao Jing, Cui Yu-Xia
Department of Pediatrics, Guizhou People's Hospital, Guiyang 550002, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2017 Nov;19(11):1174-1179. doi: 10.7499/j.issn.1008-8830.2017.11.010.
To investigate the significance of flexible bronchoscopy in children with respiratory diseases.
A retrospective analysis was performed for the clinical data of 80 children who were hospitalized due to respiratory diseases (including severe pneumonia, Mycoplasma pneumoniae pneumonia with atelectasis/lung consolidation/local emphysema, protracted pneumonia, coughing and wheezing of unknown cause, chronic cough of unknown cause, and laryngeal stridor) and who underwent flexible bronchoscopy/alveolar lavage.
Bronchoscopy found that all the 80 children had endobronchial inflammation, among whom 28 children had severe airway obstruction by secretion. Twenty-four children had congenital airway dysplasia besides endobronchial inflammation, and three children had bronchial foreign bodies. In the children with coughing and wheezing of unknown cause and laryngeal stridor, some had congenital airway dysplasia or bronchial foreign bodies. Among the 27 children with Mycoplasma pneumoniae pneumonia, 26 had severe airway obstruction/embolization by secretion; 25 children (93%) underwent chest imaging again at 2 weeks after alveolar lavage, and the results showed complete or partial lung recruitment. Among the 80 children who underwent bronchoscopy, 3 had severe hypoxemia during surgery, 1 had epistaxis, 1 had minor bleeding during alveolar lavage, 3 had transient bronchospasm, and 5 had postoperative fever; these children were all improved after symptomatic treatment.
Flexible bronchoscopy is safe and reliable in children with respiratory diseases. Early alveolar lavage under a flexible bronchoscope is recommended for children with severe/refractory Mycoplasma pneumoniae pneumonia to improve prognosis. Flexible bronchoscopy is recommended for children with recurrent coughing and wheezing and persistent laryngeal stridor, in order to directly observe the throat and airway under an endoscope.
探讨纤维支气管镜检查在儿童呼吸系统疾病中的意义。
对80例因呼吸系统疾病住院(包括重症肺炎、支原体肺炎合并肺不张/肺实变/局限性肺气肿、迁延性肺炎、不明原因咳嗽喘息、不明原因慢性咳嗽、喉喘鸣)并接受纤维支气管镜检查/肺泡灌洗的儿童临床资料进行回顾性分析。
支气管镜检查发现80例患儿均有支气管内炎症,其中28例患儿因分泌物导致严重气道阻塞。除支气管内炎症外,24例患儿存在先天性气道发育异常,3例患儿有支气管异物。在不明原因咳嗽喘息和喉喘鸣的患儿中,部分存在先天性气道发育异常或支气管异物。27例支原体肺炎患儿中,26例因分泌物导致严重气道阻塞/栓塞;25例患儿(93%)在肺泡灌洗后2周再次进行胸部影像学检查,结果显示肺复张完全或部分复张。80例接受支气管镜检查的患儿中,3例在手术过程中出现严重低氧血症,1例鼻出血,1例肺泡灌洗时少量出血,3例短暂性支气管痉挛,5例术后发热;经对症治疗后这些患儿均好转。
纤维支气管镜检查在儿童呼吸系统疾病中安全可靠。对于重症/难治性支原体肺炎患儿,建议早期在纤维支气管镜下进行肺泡灌洗以改善预后。对于反复咳嗽喘息和持续性喉喘鸣的患儿,建议进行纤维支气管镜检查,以便在内镜下直接观察咽喉和气道。