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下颈椎前路经椎间盘轴向螺钉固定:一项生物力学研究。

Anterior Transdiscal Axial Screw Fixation for Subaxial Cervical Spine: A Biomechanical Study.

作者信息

Zheng Minghui, Ji Wei, Zou Lin, Huang Zhiping, Zhu Qingan, Qu Dongbin

机构信息

Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.

出版信息

World Neurosurg. 2018 Feb;110:e459-e464. doi: 10.1016/j.wneu.2017.11.008. Epub 2017 Nov 10.

Abstract

OBJECTIVE

To evaluate stability of anterior transdiscal axial screw (ATAS) fixation for anterior instrumentation and to compare with standard anterior cervical decompression and fusion and plate (ACDFP) fixation in human subaxial cervical spine.

METHODS

Flexibility tests were conducted on 7 cadaveric specimens (C5-T1) in an intact and injured state and instrumented with ACDFP fixation, ATAS fixation, and ACDFP plus ATAS fixation at the C6-7 segment after section of the anterior and posterior longitudinal ligaments and discectomy. A pure moment of ±2.0 N-m was applied to the specimen in flexion-extension, lateral bending, and axial rotation. Range of motion (ROM) and neutral zone were calculated for the C6-7 segment.

RESULTS

ROM was reduced significantly compared with the intact or injured condition for 3 configurations under all motions. ATAS fixation resulted in similar ROM in C6-7 compared with ACDFP fixation in flexion (2.7° vs. 2.6°, P = 0.419), extension (2.7° vs. 2.1°, P = 0.152), and lateral bending (4.6° vs. 4.2°, P = 0.295) but larger ROM in axial rotation (6.1° vs. 5.3°, P = 0.014). When combined with an anterior plate, ATAS fixation reduced ROM to 1.2° in flexion, 1.1° in extension, 3.3° in lateral bending, and 3.8° in axial rotation, which were significantly smaller than ACDFP or ATAS fixation alone.

CONCLUSIONS

ATAS fixation is a biomechanically effective alternative or supplemental method of anterior fixation in subaxial cervical spine.

摘要

目的

评估经椎间盘前路轴向螺钉(ATAS)固定用于前路器械植入的稳定性,并与标准的颈椎前路减压融合钢板(ACDFP)固定在人体下颈椎进行比较。

方法

对7个尸体标本(C5-T1)在完整和损伤状态下进行灵活性测试,在切断前、后纵韧带并切除椎间盘后,于C6-7节段分别采用ACDFP固定、ATAS固定以及ACDFP联合ATAS固定。在标本上施加±2.0 N·m的纯力矩,使其进行屈伸、侧弯和轴向旋转运动。计算C6-7节段的活动范围(ROM)和中性区。

结果

在所有运动状态下,与完整或损伤状态相比,三种固定方式下的ROM均显著降低。在屈伸(2.7°对2.6°,P = 0.419)、伸展(2.7°对2.1°,P = 0.152)和侧弯(4.6°对4.2°,P = 0.295)时,ATAS固定导致的C6-7节段ROM与ACDFP固定相似,但在轴向旋转时ROM更大(6.1°对5.3°,P = 0.014)。当与前路钢板联合使用时,ATAS固定使屈伸时的ROM降至1.2°,伸展时为1.1°,侧弯时为3.3°,轴向旋转时为3.8°,显著小于单独使用ACDFP或ATAS固定。

结论

ATAS固定是下颈椎前路固定的一种生物力学有效的替代或补充方法。

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