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羊膜和全厚皮片在眼睑交界痣重建中的作用。

Role of amniotic membrane and full-thickness skin graft in reconstruction of kissing nevus of eyelids.

作者信息

Singh Manpreet, Gautam Natasha, Kaur Manpreet, Zadeng Zoramthara

机构信息

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Ophthalmol. 2017 Nov;65(11):1219-1221. doi: 10.4103/ijo.IJO_407_17.

Abstract

A 20-year-old girl presented with a large pigmented lesion over the temporal aspect of left lateral canthus involving the lateral one-third of both eyelids, since birth. A slow increase in its size had been noticed for the past 2 years. On examination, a hairy nevus measuring 34 mm × 22 mm was noticed involving left eyelid skin, the mucocutaneous junction (MCJ), palpebral conjunctiva, and lateral canthus. The surface was irregularly thick and covered with long, thick, and pigmented hairs. A clinical diagnosis of kissing nevus of eyelids was kept and a surgical resection with reconstruction planned. A customized full-thickness skin graft (FTSG) and amniotic membrane grafts (AMGs) were used for the reconstruction of cutaneous and MCJ, respectively. Histopathology showed the features of junctional nevus. At 4 months of follow-up, a well taken FTSG and healthy/sharp MCJ were noticed with no recurrence. We advocate a possible role of AMG, particularly in the reconstruction of the conjunctival mucosa and MCJ.

摘要

一名20岁女孩自出生以来,左外眦颞侧出现一个大的色素沉着病变,累及双侧眼睑的外侧三分之一。在过去2年中,发现其大小缓慢增加。检查时,发现一个大小为34 mm×22 mm的毛发痣,累及左眼睑皮肤、黏膜皮肤交界处(MCJ)、睑结膜和外眦。表面不规则增厚,覆盖着长而粗的色素沉着毛发。临床诊断为眼睑接吻痣,并计划进行手术切除及重建。分别使用定制的全厚皮片(FTSG)和羊膜移植片(AMG)对皮肤和MCJ进行重建。组织病理学显示为交界痣的特征。随访4个月时,可见移植的FTSG情况良好,MCJ健康/边界清晰,无复发。我们提倡AMG可能发挥的作用,特别是在结膜黏膜和MCJ的重建中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ac/5700600/27325ffcff25/IJO-65-1219-g001.jpg

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