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前弹力层膨出:一种独特的临床实体。

Predescemetocele: A distinct clinical entity.

作者信息

Narang Priya, Agarwal Amar, Kumar Dhivya Ashok

机构信息

Narang Eye Care and Laser Centre, Ahmedabad, Gujarat, India.

Dr. Agarwal's Eye Hospital and Research Centre, Chennai, Tamil Nadu, India.

出版信息

Indian J Ophthalmol. 2017 Nov;65(11):1224-1226. doi: 10.4103/ijo.IJO_492_17.

DOI:10.4103/ijo.IJO_492_17
PMID:29133660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5700602/
Abstract

The case report incorporates a Fourier-domain optical coherence tomography (OCT) examination for demonstration of the existence of pre-Descemet's layer (PDL; Dua's layer) overlying a descemetocele and demonstrates predescemetocele as a separate clinical entity. The prospective analysis was done in two cases that had descemetocele, and OCT demonstrated the presence of PDL over an unruptured descemetocele that offers resilience and can be treated with an elective deep anterior lamellar keratoplasty or a penetrating keratoplasty. A descemetocele, when covered with PDL, should be correctly designated as a predescemetocele. Loss of PDL leads to baring of Descemet's membrane that eventually ruptures.

摘要

该病例报告纳入了傅里叶域光学相干断层扫描(OCT)检查,以证明覆盖在角膜后弹力层膨出上方的前弹力层下膜(PDL;杜阿氏层)的存在,并将前弹力层下膨出证明为一种独立的临床实体。对两例患有角膜后弹力层膨出的病例进行了前瞻性分析,OCT显示在未破裂的角膜后弹力层膨出上方存在PDL,其具有弹性,可通过选择性深层前板层角膜移植术或穿透性角膜移植术进行治疗。当角膜后弹力层膨出被PDL覆盖时,应正确地将其指定为前弹力层下膨出。PDL的缺失会导致角膜后弹力层暴露,最终破裂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a07/5700602/6f1874901cd9/IJO-65-1224-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a07/5700602/8eaf88a1d0db/IJO-65-1224-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a07/5700602/6f1874901cd9/IJO-65-1224-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a07/5700602/8eaf88a1d0db/IJO-65-1224-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a07/5700602/6f1874901cd9/IJO-65-1224-g002.jpg

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本文引用的文献

1
Deep anterior lamellar keratoplasty--triple procedure: a useful clinical application of the pre-Descemet's layer (Dua's layer).深前板层角膜移植术——三联手术:Descemet膜前层(杜阿层)的一种实用临床应用
Eye (Lond). 2015 Mar;29(3):323-6. doi: 10.1038/eye.2014.273. Epub 2014 Oct 31.
2
Pre-Descemet's endothelial keratoplasty (PDEK).前板层角膜内皮移植术(PDEK)。
Br J Ophthalmol. 2014 Sep;98(9):1181-5. doi: 10.1136/bjophthalmol-2013-304639. Epub 2014 Mar 21.
3
Author reply: To PMID 23714320.
Indian J Ophthalmol. 2022 May;70(5):1564-1570. doi: 10.4103/ijo.IJO_3070_21.
Ophthalmology. 2014 May;121(5):e25-6. doi: 10.1016/j.ophtha.2013.12.020. Epub 2014 Feb 20.
4
Human corneal anatomy redefined: a novel pre-Descemet's layer (Dua's layer).人类角膜解剖结构的重新定义:一种新的前 Descemet 膜(Dua 层)。
Ophthalmology. 2013 Sep;120(9):1778-85. doi: 10.1016/j.ophtha.2013.01.018. Epub 2013 May 25.
5
Modified deep anterior lamellar keratoplasty in the management of small and large epithelialized descemetoceles.改良深层前板层角巩膜移植术治疗小和大的上皮化角膜内皮囊肿。
Cornea. 2011 Oct;30(10):1179-82. doi: 10.1097/ICO.0b013e3182031c81.
6
Deep anterior lamellar keratoplasty with phacoemulsification.超声乳化白内障吸除联合深板层角膜移植术。
J Cataract Refract Surg. 2011 Jan;37(1):122-6. doi: 10.1016/j.jcrs.2010.07.031.
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Surgical technique of deep anterior lamellar keratoplasty in descemetoceles.深板层角膜内皮移植术治疗角膜后弹力层膨出。
Cornea. 2010 Dec;29(12):1448-51. doi: 10.1097/ICO.0b013e3181e2ef9c.
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