Canbay Fatma, Yılmaz Aydın, Öztürk Ayperi, Aktaş Zafer, Tatcı Ebru
Clinic of Inverventional Pulmonology, Ankara Ataturk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara,Turkey.
Division of Nucleer Medicine, Ankara Ataturk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey.
Tuberk Toraks. 2017 Sep;65(3):245-248. doi: 10.5578/tt.46474.
Relapsing polychondritis (RP) is a rare autoimmune disease, characterized by episodic inflammatory attacks on cartilaginous tissue. Elastic cartilage of the ears and nose, hyaline cartilage of the peripheral joints, vertebral fibrocartilage, tracheobronchial cartilage, and tissues rich in proteoglycan such as those in the eyes, heart, blood vessels, and inner ear are more likely to be affected. A 35-year-old male presented with complaints of hoarseness, tinnitus and dyspnea for 19 years, with a history of several diagnostic and therapeutic interventions for laryngeal and respiratory tract. He was diagnosed to have inflammation of the tracheobronchial cartilage, cardiac valvulopathy and conductive hearing loss after intensive diagnostic studies. He responded well to low-dose steroids in combination with methotrexate. RP is a diagnostically challenging condition and may cause significant morbidities during diagnosis. RP should be considered in differential diagnosis of airway obstruction as a rare condition.
复发性多软骨炎（RP）是一种罕见的自身免疫性疾病，其特征为对软骨组织的发作性炎性攻击。耳朵和鼻子的弹性软骨、外周关节的透明软骨、椎体纤维软骨、气管支气管软骨以及富含蛋白聚糖的组织，如眼睛、心脏、血管和内耳中的组织，更容易受到影响。一名35岁男性因声音嘶哑、耳鸣和呼吸困难19年就诊，有多次针对喉和呼吸道的诊断及治疗经历。经过深入诊断研究，他被诊断为气管支气管软骨炎症、心脏瓣膜病和传导性听力损失。他对低剂量类固醇联合甲氨蝶呤反应良好。RP是一种诊断具有挑战性的疾病，在诊断过程中可能导致严重发病。作为一种罕见疾病，在气道梗阻的鉴别诊断中应考虑RP。
