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中国多发性骨髓瘤诊断与治疗指南(2017年修订版)

[The guidelines for the diagnosis and management of multiple myeloma in China (2017 revision)].

出版信息

Zhonghua Nei Ke Za Zhi. 2017 Nov 1;56(11):866-870. doi: 10.3760/cma.j.issn.0578-1426.2017.11.021.

Abstract

Multiple myeloma (MM) is a clonal plasma cell malignancy, mainly in elderly people and still incurable at present. In the ear of novel agents and sensitive laboratory exams, the diagnosis and treatment of MM have been significantly improved. Chinese MM guidelines for the diagnosis and treatment were updated every two years according to the progression of international and domestic research and clinical studies. In this version, we updated the response criteria and new combination regimens in newly diagnosed patients. Monoclonal gammopathy of renal significance (MGRS) was added as a new part of differential diagnosis, meanwhile, relapsed/refractory MM patients should be treated as long as possible.

摘要

多发性骨髓瘤(MM)是一种克隆性浆细胞恶性肿瘤,主要发生于老年人,目前仍无法治愈。在新型药物和敏感实验室检查出现后,MM的诊断和治疗有了显著改善。中国MM诊断与治疗指南根据国际国内研究及临床研究进展每两年更新一次。在本版中,我们更新了新诊断患者的疗效标准和新的联合治疗方案。具有肾意义的单克隆丙种球蛋白病(MGRS)作为鉴别诊断的新内容被纳入,同时,复发/难治性MM患者应尽可能接受治疗。

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