Cai Y M, Song Y J, Liu H, Hong F C
Sexually Transmitted Disease Control and Prevention Department, Shenzhen Center for Chronic Disease Control and Prevention, Shenzhen 518020, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2017 Nov 6;51(11):994-1000. doi: 10.3760/cma.j.issn.0253-9624.2017.11.008.
To investigate the factors associated with syphilis/HIV infection among men who have sex with men (MSM) maintaining a single sexual partner in Shenzhen. Respondent driven sampling and snowball sampling method were used to recruit MSM receiving voluntary counseling and testing in Shenzhen Rainbow clinic from 2011 to 2016.
aged 18 years and above; reported having one or more anal sexual partners in the recent 6 months. A total of 3 109 men who have sex with men (MSM) were involved in the study. Questionnaire-based interviews were conducted on a one-on-one basis. Data were collected including socio-demographic information, human immunodeficiency virus (HIV) testing history, history of blood donation and drug abuse in the recent two years, self-identified sexual orientation, role in homosexual behavior, ever being money boys (MB) and clients of MB, female sexual partners in the recent 6 months. 5 ml blood samples were taken after questionnaires. Syphilis was screened using toluidine red unheated serum test for the antibody of treponema pallidum and then confirmed by treponema pallidum particle assay. The enzyme-linked immunosorbent assay (ELISA) was used for screening HIV and western blot was used to confirm the HIV screening results. The difference of condom use among MSM between female sexual partners and male sexual partners were compared. Multivariate unconditional stepwise logistic regression model was used to analyze factors associated with syphilis infection and HIV positive among MSM. A total of 3 109 eligible participants with mean (SD) age of 31.49 (8.64) years were enrolled in this study. Among them, 565 cases were infected with syphilis (18.17%), 330 cases were infected with HIV (10.61%), and 165 cases (5.31%) were syphilis co-infected with HIV. 791 (25.44%) reported maintaining a single sexual partners in the recent 6 months. Compared to MSM with multiple sexual partners, the prevalence of syphilis and HIV infection among MSM with a single sexual partner were lower, and the (95%) were 0.64 (0.51-0.81) and 0.66 (0.49-0.90), respectively. The proportion of fixed single sexual partner was much lower among MSM in Shenzhen. Maintaining a single sexual partners can reduce the risk of syphilis/HIV infection among MSM.
调查深圳保持单一性伴侣的男男性行为者（MSM）中梅毒/艾滋病毒感染的相关因素。采用应答者驱动抽样和滚雪球抽样方法，招募2011年至2016年在深圳彩虹诊所接受自愿咨询和检测的男男性行为者。
年龄18岁及以上；报告在最近6个月内有一个或多个肛交性伴侣。共有3109名男男性行为者参与了该研究。采用一对一的问卷调查访谈方式。收集的数据包括社会人口学信息、人类免疫缺陷病毒（HIV）检测史、近两年的献血史和药物滥用史、自我认同的性取向、在同性恋行为中的角色、曾为男妓（MB）及男妓的客户、最近6个月内的女性性伴侣。问卷调查后采集5毫升血样。梅毒采用甲苯胺红不加热血清试验筛查梅毒螺旋体抗体，然后用梅毒螺旋体颗粒凝集试验确诊。采用酶联免疫吸附试验（ELISA）筛查HIV，用免疫印迹法确认HIV筛查结果。比较男男性行为者与女性性伴侣和男性性伴侣发生性行为时使用避孕套的差异。采用多变量无条件逐步逻辑回归模型分析男男性行为者中梅毒感染和HIV阳性的相关因素。本研究共纳入3109名符合条件的参与者，平均（标准差）年龄为31.49（8.64）岁。其中，565例感染梅毒（18.17%），330例感染HIV（10.61%），165例（5.31%）梅毒合并HIV感染。791例（25.44%）报告在最近6个月内保持单一性伴侣。与有多个性伴侣的男男性行为者相比，有单一性伴侣的男男性行为者中梅毒和HIV感染的患病率较低，比值比（95%可信区间）分别为0.64（0.51 - 0.81）和0.66（0.49 - 0.90）。深圳男男性行为者中固定单一性伴侣的比例要低得多。保持单一性伴侣可降低男男性行为者中梅毒/艾滋病毒感染的风险。
