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以主动脉夹层为首发表现的大动脉炎病例报告。

A case report of Takayasu arteritis with aortic dissection as initial presentation.

作者信息

Guo JiGuang, Zhang GuoWu, Tang Dan, Zhang JianBin

机构信息

Department of Nephrology Department of Vascular Surgery, YongChuan Hospital of ChongQing Medical University, ChongQing, China.

出版信息

Medicine (Baltimore). 2017 Nov;96(45):e8610. doi: 10.1097/MD.0000000000008610.

Abstract

RATIONALE

The initial symptoms and signs of Takayasu arteritis vary due to the heterogeneity of affected vessels. Moreover, the vascular lesions are difficult to detect at initial presentation, making diagnosis even more challenging. Although cases of aortic dissection with arteritis history have been reported, Takayasu arteritis in men with aortic dissection as initial presentation is very rare.

PATIENT CONCERNS

A 37-year-old man presenting with persistent chest and back pain for 6 days was transferred to our hospital for further treatment. Left hand pulse was absent and right lower limb pulse was feeble. Blood pressure was 144/83 mmHg in the right arm but only 114/62 mmHg in the left arm.

DIAGNOSES

Computed tomography angiography revealed aortic dissection (DeBakey type III b) from the descending aorta to the distal abdominal aorta.

INTERVENTIONS

High-dose glucocorticoid therapy and immunosuppressive therapy have been used to control inflammatory reaction during acute period of Takayasu arteritis. Endovascular graft exclusion (EVGE) surgery was performed to cover the primary entry tear and re-expand true lumen during inactive stage.

OUTCOMES

His pain symptoms improved progressively and he was followed in our outpatient clinic after discharged from hospital, without recurrence.

LESSONS

Timely therapy (glucocorticoid and immunosuppressive) and corrective surgery (endovascular graft exclusion) for Takayasu arteritis with aortic dissection at the inactive stage is essential and beneficial.

摘要

理论依据

由于受累血管的异质性,高安动脉炎的初始症状和体征各不相同。此外,血管病变在初次就诊时难以检测到,这使得诊断更具挑战性。虽然有报道称有动脉炎病史的患者发生主动脉夹层,但以主动脉夹层为初始表现的男性高安动脉炎非常罕见。

患者情况

一名37岁男性,持续胸痛和背痛6天,被转至我院进一步治疗。左手脉搏消失,右下肢脉搏微弱。右臂血压为144/83mmHg,而左臂仅为114/62mmHg。

诊断

计算机断层扫描血管造影显示主动脉夹层(DeBakey III b型),从降主动脉至腹主动脉远端。

干预措施

在高安动脉炎急性期,使用大剂量糖皮质激素治疗和免疫抑制治疗来控制炎症反应。在非活动期进行血管腔内移植物置入术(EVGE)以覆盖原发破口并使真腔再扩张。

结果

他的疼痛症状逐渐改善,出院后在我院门诊随访,无复发。

经验教训

对于处于非活动期的伴有主动脉夹层的高安动脉炎,及时进行治疗(糖皮质激素和免疫抑制治疗)和矫正手术(血管腔内移植物置入术)至关重要且有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1059/5690782/e1fc1df56c0d/medi-96-e8610-g001.jpg

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