Cunningham C C, Lind S E
Hematology-Oncology Unit, Massachusetts General Hospital, Boston 02114.
Am J Hematol. 1989 Feb;30(2):112-3. doi: 10.1002/ajh.2830300211.
Post transfusion purpura (PTP) is a rare disorder characterized by the abrupt onset of severe thrombocytopenia following transfusion. A patient with PTP and massive bleeding was refractory to corticosteroids, gamma globulin, and plasma exchange but developed an immediate and sustained rise in platelet count following splenectomy. Splenectomy may be a useful therapeutic modality in patients with refractory PTP.
输血后紫癜(PTP)是一种罕见的疾病,其特征为输血后突然发生严重血小板减少。一名患有PTP并伴有大量出血的患者对皮质类固醇、γ球蛋白和血浆置换治疗无效,但脾切除术后血小板计数立即且持续上升。脾切除术对于难治性PTP患者可能是一种有效的治疗方式。