Pediatric Emergency Medicine, Vanderbilt University Medical Center, Monroe Carell Jr. Childrens' Hospital, Nashville, TN, United States.
Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Am J Emerg Med. 2018 May;36(5):769-773. doi: 10.1016/j.ajem.2017.10.009. Epub 2017 Oct 6.
Acute asthma exacerbations (AAE) account for many Pediatric Emergency Department (PED) visits. Chest radiography (CXR) is often performed in these patients to identify practice-changing findings such as pneumonia (PNA). Limited knowledge exists to balance the cost and radiation dose of CXR with expected yield of clinically meaningful information.
To determine in children with AAE with CXR, whether patient characteristics are associated with radiographic PNA; and significant practice change by initiation of antibiotic.
DESIGN/METHODS: Retrospective chart review of AAE patients with CXR performed in a PED in 2014. We examined univariate associations between patient characteristics and PNA on CXR and administration of antibiotic. Multiple logistic regression models then subsequently examined adjusted associations between patient characteristics and both outcomes.
Of 288 patients, 43 (15%) had PNA on CXR and 51 (17.8%) received antibiotics. There were no statistically significant univariate associations between either outcome and age, race, gender, insurance status, mode of PED arrival, fever or hypoxia (all p>0.11). Crackles were associated with antibiotic administration (p=0.03), but not PNA on CXR (p=0.07). Only previous antibiotic use within 7days had both significant univariate associations (p=0.002) and adjusted associations with both PNA on CXR (aOR 3.6) and antibiotic administration (aOR 3.3).
CXR infrequently adds valuable information in children with AAE. Patients treated with antibiotic within 7days are more likely to have PNA identified on CXR and receive antibiotics. A larger study is needed to examine potential significance of hypoxia and crackles.
急性哮喘加重(AAE)是小儿急诊科(PED)就诊的主要原因。在这些患者中,通常会进行胸部 X 光检查(CXR)以确定改变实践的发现,例如肺炎(PNA)。对于平衡 CXR 的成本和辐射剂量与临床有意义信息的预期收益,目前知识有限。
在患有 CXR 的 AAE 患儿中,确定患者特征是否与放射学 PNA 相关;以及抗生素的使用是否会导致显著的实践改变。
设计/方法:对 2014 年在 PED 进行 CXR 的 AAE 患者进行回顾性图表审查。我们检查了患者特征与 CXR 上 PNA 以及抗生素使用之间的单变量关联。随后,多变量逻辑回归模型检查了患者特征与这两个结果之间的调整关联。
在 288 名患者中,有 43 名(15%)在 CXR 上有 PNA,51 名(17.8%)接受了抗生素治疗。在这两个结果中,年龄、种族、性别、保险状况、PED 到达方式、发热或缺氧等因素均无统计学显著的单变量关联(所有 p>0.11)。湿啰音与抗生素使用相关(p=0.03),但与 CXR 上的 PNA 无关(p=0.07)。只有在 7 天内使用过抗生素这一因素与 CXR 上的 PNA 以及抗生素使用均具有显著的单变量关联(p=0.002)和调整关联(CXR 上的 PNA:aOR 3.6;抗生素使用:aOR 3.3)。
在患有 AAE 的儿童中,CXR 很少提供有价值的信息。在 7 天内接受抗生素治疗的患者更有可能在 CXR 上发现 PNA 并接受抗生素治疗。需要进行更大的研究来检查缺氧和湿啰音的潜在意义。