Maisel J M, Pearlstein C S, Adams W H, Heotis P M
Department of Ophthalmology, School of Medicine, State University of New York, Stony Brook.
Am J Ophthalmol. 1989 Feb 15;107(2):145-50. doi: 10.1016/0002-9394(89)90213-4.
On routine examination, asymptomatic patients from the Marshall Islands were noted to have large optic disks associated with high cup/disk ratios and normal intraocular pressure. We retrospectively analyzed color fundus photographs of 54 eyes and 22 eyes of 15 patients had optic disks greater than 2.10 mm, or megalopapilla. Of 36 patients with cup/disk ratios exceeding 0.6, 31 (86%) had visual acuities of better than or equal to 20/30. The optic nerve rim and disk areas varied directly as did disk and cup diameters. Three large disks with an 18-year photographic follow-up showed no change. Optic disk characteristics can vary widely among genetically isolated populations.
在常规检查中，发现来自马绍尔群岛的无症状患者有视盘增大，杯盘比高且眼压正常。我们回顾性分析了54只眼的彩色眼底照片，15例患者中有22只眼的视盘直径大于2.10mm，即存在视盘过大。在杯盘比超过0.6的36例患者中，31例（86%）的视力优于或等于20/30。视神经边缘和视盘面积与视盘及杯盘直径呈正比变化。对3个大视盘进行了18年的摄影随访，结果显示无变化。在基因隔离人群中，视盘特征可能有很大差异。
