Darwiche K, Özkan F, Wolters C, Eisenmann S
Pneumologie. 2017 Nov;71(11):798-812. doi: 10.1055/s-0043-103034. Epub 2017 Nov 13.
Endobronchial Ultrasound (EBUS) with the two modalities curved and radial EBUS significantly improved the diagnostics in several pulmonary diseases. The examination and staging of mediastinal and hilar lymph nodes in patients with known or suspected lung malignancy as well as the evaluation of unknown pulmonary or mediastinal lesions can be achieved with minimal invasive means when using EBUS. More invasive surgical procedures for diagnostic purposes can be omitted. The diagnostic yield also increases when EBUS is applied in sarcoidosis or mediastinal lymph node tuberculosis but only to some extend in case of lymphoma. Samples obtained by EBUS-TBNA should be handled efficiently to allow molecular analysis in lung cancer. EBUS is a safe procedure, and complication rate is extremely low. Further advances of the EBUS technology focus on improving analysis of the information provided by the ultrasound image and a better tissue sampling by developing of new EBUS bronchoscopes and TBNA-needles.
带有弯曲型和径向型两种模式的支气管内超声（EBUS）显著改善了多种肺部疾病的诊断。对于已知或疑似肺部恶性肿瘤患者的纵隔和肺门淋巴结检查及分期，以及对不明肺部或纵隔病变的评估，使用EBUS时可以通过微创手段实现。可以省去用于诊断目的的更具侵入性的外科手术。当EBUS应用于结节病或纵隔淋巴结结核时，诊断率也会提高，但在淋巴瘤病例中仅能提高到一定程度。通过EBUS-TBNA获得的样本应妥善处理，以便进行肺癌的分子分析。EBUS是一种安全的操作，并发症发生率极低。EBUS技术的进一步发展集中在通过开发新型EBUS支气管镜和TBNA针来改进对超声图像提供的信息的分析以及更好地进行组织采样。
