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越南病理学家改善血液病理学诊断机会的评估。

Evaluation of Opportunities to Improve Hematopathology Diagnosis for Vietnam Pathologists.

作者信息

Dayton Vanessa, Nguyen Chi Kim, Van Trinh Thu, Thanh Nguyen Van, To Ta Van, Hung Nguyen Phi, Dung Nguyen Ngoc, Milner Danny A

机构信息

Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis.

Pensacola Pathologists, Pensacola, FL.

出版信息

Am J Clin Pathol. 2017 Nov 20;148(6):529-537. doi: 10.1093/ajcp/aqx108.

Abstract

OBJECTIVES

We evaluate the need for, feasibility of, and impediments to improving hematopathology diagnoses for cancer hospitals in Vietnam.

METHODS

Two hematopathologists from the United States visited three major cancer treatment hospitals in Vietnam to workshop a sampling of difficult hematopathology cases. With Vietnamese pathologists, they toured histopathology, immunohistochemistry, and ancillary laboratory facilities.

RESULTS

Automated tissue processors and slide staining equipment were documented for each of the three hospitals. Between seven and 11 hematopathology cases were reviewed for each hospital. Exact/complete diagnostic concordance was 50% or less for all three laboratories. The major impediments to accurate specific diagnoses were limitations of immunohistochemical stains, limited stains available in house, and, for one of the hospitals, difficulty with interpretation of the immunohistochemistry.

CONCLUSIONS

Vietnamese pathologists would benefit from hematopathology training or opportunities to consult with hematopathologists in the United States. Expert hematopathology consultation services are currently unavailable within Vietnam, as postgraduate training for laboratory physicians consists of residency training in anatomic pathology only. Limitations in the quality of histopathology and immunohistochemistry could impose a barrier to success of efforts to improve hematopathology diagnosis. Implementation of a histopathology and immunohistochemistry quality improvement program might overcome this limitation.

摘要

目的

我们评估了越南癌症医院改善血液病理学诊断的必要性、可行性及障碍。

方法

两名来自美国的血液病理学家访问了越南的三家主要癌症治疗医院,就一些疑难血液病理学病例进行研讨。他们与越南病理学家一同参观了组织病理学、免疫组织化学及辅助实验室设施。

结果

记录了三家医院各自的自动组织处理仪和玻片染色设备。每家医院审查了7至11例血液病理学病例。所有三个实验室的准确/完全诊断一致性均为50%或更低。准确做出特定诊断的主要障碍包括免疫组织化学染色的局限性、内部可用染色剂有限,以及其中一家医院在免疫组织化学解读方面存在困难。

结论

越南病理学家将受益于血液病理学培训或与美国血液病理学家进行咨询的机会。越南目前没有专家血液病理学咨询服务,因为实验室医生的研究生培训仅包括解剖病理学住院医师培训。组织病理学和免疫组织化学质量的局限性可能会对改善血液病理学诊断的努力的成功构成障碍。实施组织病理学和免疫组织化学质量改进计划可能会克服这一局限性。

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