Pennesi Christine M, Neely John, Marks Ames G, Basak S Alison
J Drugs Dermatol. 2017 Nov 1;16(11):1156-1158.
Atopic dermatitis and prurigo nodularis result from complex interactions between the skin, the immune system, and the external environment. The pruritus associated with these conditions greatly impacts patients' quality of life and lacks uniformly effective treatment. A 57-year-old patient presented with severe atopic dermatitis and subsequent prurigo nodularis refractory to numerous standard therapies. The supplement isoquercetin was initiated and he noted significant, sustained reduction in his pruritus after only four weeks. Isoquercetin is a glycoside derivative with antihistamine properties of quercetin, a natural polyphenol flavonoid found in many plants. It may offer itch relief in patients who have failed more conventional therapies.
J Drugs Dermatol. 2017;16(11):1156-1158.
.特应性皮炎和结节性痒疹是皮肤、免疫系统和外部环境之间复杂相互作用的结果。与这些病症相关的瘙痒严重影响患者的生活质量，且缺乏统一有效的治疗方法。一名57岁的患者患有严重的特应性皮炎，随后出现结节性痒疹，对多种标准疗法均无效。开始使用异槲皮素补充剂后，仅四周他就注意到瘙痒显著且持续减轻。异槲皮素是一种糖苷衍生物，具有槲皮素的抗组胺特性，槲皮素是一种存在于许多植物中的天然多酚类黄酮。对于那些传统疗法无效的患者，它可能有助于缓解瘙痒。
《皮肤药物学杂志》。2017年；16(11):1156 - 1158。
