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Exposing the deadly dark side of apoptotic cancer stem cells.

作者信息

Jinesh Goodwin G

机构信息

Department of Urology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

出版信息

Oncoscience. 2017 Oct 23;4(9-10):124-125. doi: 10.18632/oncoscience.369. eCollection 2017 Sep.

DOI:10.18632/oncoscience.369
PMID:29142901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5672894/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe08/5672894/d34f56921928/oncoscience-04-0124-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe08/5672894/d34f56921928/oncoscience-04-0124-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe08/5672894/d34f56921928/oncoscience-04-0124-g001.jpg

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本文引用的文献

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The Blebbishield Emergency Program Overrides Chromosomal Instability and Phagocytosis Checkpoints in Cancer Stem Cells.Blebbishield 紧急计划会绕过癌症干细胞中的染色体不稳定性和吞噬作用检查点。
Cancer Res. 2017 Nov 15;77(22):6144-6156. doi: 10.1158/0008-5472.CAN-17-0522. Epub 2017 Aug 30.
2
Pim kinase isoforms: devils defending cancer cells from therapeutic and immune attacks.Pim激酶亚型：保护癌细胞免受治疗和免疫攻击的“恶魔”
Apoptosis. 2016 Nov;21(11):1203-1213. doi: 10.1007/s10495-016-1289-3.
3
Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis.
Mutant p53s and chromosome 19 microRNA cluster overexpression regulate cancer testis antigen expression and cellular transformation in hepatocellular carcinoma.
突变型 p53 和 19 号染色体微小 RNA 簇过表达调节肝癌中癌睾丸抗原的表达和细胞转化。
Sci Rep. 2021 Jun 16;11(1):12673. doi: 10.1038/s41598-021-91924-7.
4
Targeting K-Ras and apoptosis-driven cellular transformation in cancer.靶向癌症中K-Ras和凋亡驱动的细胞转化
Cell Death Discov. 2021 Apr 14;7(1):80. doi: 10.1038/s41420-021-00457-5.
5
Regulation of MYO18B mRNA by a network of C19MC miRNA-520G, IFN-γ, CEBPB, p53 and bFGF in hepatocellular carcinoma.C19MC miRNA-520G、IFN-γ、CEBPB、p53 和 bFGF 调控网络对肝癌中 MYO18B mRNA 的调控。
Sci Rep. 2020 Jul 23;10(1):12371. doi: 10.1038/s41598-020-69179-5.
6
Chromosome 19 miRNA cluster and CEBPB expression specifically mark and potentially drive triple negative breast cancers.19 号染色体 miRNA 簇和 CEBPB 表达特异性标记并可能驱动三阴性乳腺癌。
PLoS One. 2018 Oct 18;13(10):e0206008. doi: 10.1371/journal.pone.0206008. eCollection 2018.
7
Apoptosis: A Target for Anticancer Therapy.细胞凋亡：抗癌治疗的新靶点。
Int J Mol Sci. 2018 Feb 2;19(2):448. doi: 10.3390/ijms19020448.
线粒体寡聚体增强癌症干细胞中的糖酵解，以促进凋亡后肌动蛋白防护介导的转化。
Cell Death Discov. 2016 Feb 1;2:16003. doi: 10.1038/cddiscovery.2016.3. eCollection 2016.
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Cell Death Discov. 2016;2:15069-. doi: 10.1038/cddiscovery.2015.69. Epub 2016 Jan 25.
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Sci Rep. 2016 Apr 4;6:23965. doi: 10.1038/srep23965.
6
Smac mimetic with TNF-α targets Pim-1 isoforms and reactive oxygen species production to abrogate transformation from blebbishields.与肿瘤坏死因子-α作用的Smac模拟物靶向Pim-1亚型和活性氧生成，以消除来自肌动蛋白小体的转化。
Biochem J. 2016 Jan 1;473(1):99-107. doi: 10.1042/BJ20150877. Epub 2015 Oct 27.
7
Blebbishields, the emergency program for cancer stem cells: sphere formation and tumorigenesis after apoptosis.Blebbishields，癌症干细胞的应急方案：细胞凋亡后球体形成和肿瘤发生。
Cell Death Differ. 2013 Mar;20(3):382-95. doi: 10.1038/cdd.2012.140. Epub 2012 Nov 23.