Bory C, Boulieu R, Chantin C, Mathieu M
Lab. de Biochimie, Hôpital Debrousse, Lyon, France.
Clin Chem. 1989 Feb;35(2):321-2.
In this rapid, specific, and sensitive high-performance liquid-chromatographic method of analysis for homogentisic acid in biological fluids, homogentisic acid is separated on a column of Nucleosil CN. This method, which we applied to the diagnosis of three cases of alcaptonuria, represents a suitable analytical tool for the diagnosis of alcaptonuria.
