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Homogentisic acid determined in biological fluids by HPLC.

作者信息

Bory C, Boulieu R, Chantin C, Mathieu M

机构信息

Lab. de Biochimie, Hôpital Debrousse, Lyon, France.

出版信息

Clin Chem. 1989 Feb;35(2):321-2.

PMID:2914385
Abstract

In this rapid, specific, and sensitive high-performance liquid-chromatographic method of analysis for homogentisic acid in biological fluids, homogentisic acid is separated on a column of Nucleosil CN. This method, which we applied to the diagnosis of three cases of alcaptonuria, represents a suitable analytical tool for the diagnosis of alcaptonuria.

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