Pearson Hadley J, Mosser Joy L, Jacks Stephanie K
University of Mississippi Medical Center, Jackson, MS, USA.
Nationwide Children's Hospital, Columbus, OH, USA.
Pediatr Dermatol. 2017 Nov;34(6):e305-e308. doi: 10.1111/pde.13306.
When encountered in children, xanthomas are most commonly associated with a group of disorders known as familial hyperlipidemias. Aside from cosmetic concerns, these xanthomas are typically asymptomatic, but when generalized pruritus is a prominent associated symptom, clinicians should consider a different set of diagnoses that includes cholestasis of the liver. In this article we present two illustrative cases of children with cholestatic disease, pruritus, and xanthomas and discuss other disorders that may include this triad.
儿童出现的黄瘤最常与一组称为家族性高脂血症的疾病相关。除了美观问题外，这些黄瘤通常无症状，但当全身性瘙痒成为突出的相关症状时，临床医生应考虑一系列不同的诊断，其中包括肝内胆汁淤积。在本文中，我们介绍了两例患有胆汁淤积性疾病、瘙痒和黄瘤的儿童病例，并讨论了可能包括这三联征的其他疾病。
