Silent bowel perforation occurring during corticosteroid treatment for pemphigus vulgaris.

We present the case of a patient who experienced a silent colonic perforation while being treated for pemphigus vulgaris with prednisone and azathioprine. Dermatologists are experienced in the management of pemphigus vulgaris with prednisone. We report a well-recognized but rarely reported adverse effect of this standard therapy for pemphigus vulgaris.