Walusinski Olivier
Family Physician, Private Practice, Brou, France.
Front Neurol Neurosci. 2018;41:40-49. doi: 10.1159/000475691. Epub 2017 Nov 16.
Yawning, laughing, and crying are normal physiological behaviors of humans in good health. As with all physiological behaviors, their deregulation can reveal disorders. Pathological yawning occurs in salvos of 10-20 successive yawns, and the number of yawns per day can exceed one hundred. After listing the functional etiologies, we will give the clinical keys for differentiating the most serious causes: iatrogenic, tumors, strokes, amyotrophic lateral sclerosis, and intracranial hypertension. Sudden, uncontrollable episodes of emotional display involving pathological laughing and crying (PLC) may be encountered in various neurological diseases: amyotrophic lateral sclerosis, multiple system atrophy (cerebellar), cerebrovascular disease, traumatic brain injuries, mass lesions in the cerebellopontine junction, and epilepsy. After describing the pathophysiology of PLC and the use of diagnostic scales for PLC, we will discuss the current treatments.
打哈欠、大笑和哭泣是健康人的正常生理行为。与所有生理行为一样，它们的失调可能揭示疾病。病理性打哈欠以连续10至20次的阵发形式出现，每天打哈欠的次数可能超过100次。在列出功能性病因后，我们将给出鉴别最严重病因的临床要点：医源性、肿瘤、中风、肌萎缩侧索硬化症和颅内高压。在各种神经系统疾病中可能会出现涉及病理性哭笑（PLC）的突然、无法控制的情绪发作：肌萎缩侧索硬化症、多系统萎缩（小脑型）、脑血管疾病、创伤性脑损伤、桥小脑角的占位性病变和癫痫。在描述了PLC的病理生理学以及PLC诊断量表的使用后，我们将讨论当前的治疗方法。
