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Y形支架联合碘-125粒子链治疗门静脉分支肿瘤血栓形成的肝细胞癌:1例报告

Y-configuration stent combined with iodine-125 seeds strand for the treatment of hepatocellular carcinoma with tumor thrombosis in portal vein branches: A case report.

作者信息

Tan Tan, Xiao Yudong, Zhou Shunke, Ma Cong, Zhang Zishu

机构信息

Department of Radiology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, P.R. China.

出版信息

Medicine (Baltimore). 2017 Nov;96(46):e8660. doi: 10.1097/MD.0000000000008660.

Abstract

RATIONALE

Currently, the treatment of hepatocellular carcinoma (HCC) associated with portal vein tumor thrombosis (PVTT) is a challenge. Percutaneous puncture endovascular placement of iodine-125 (I) seeds strand and stent is reported to treat HCC with tumor thrombus effectively. However, it is proved to be only suitable for the main portal vein (MPV) thrombus.

PATIENT CONCERNS

A 42-year-old male patient was referred to our institution after experiencing right upper abdominal distention without abdominal pain, nausea, or vomiting for 2 weeks. The patient had a history of hepatitis B virus infection over a 20 year period.

DIAGNOSIS

After a full evaluation, the patient was diagnosed with primary HCC with a tumor thrombus in both main and branch portal veins.

INTERVENTIONS

We used a Y-configuration stent combined with I seeds strand to treat the tumor thrombus in both main and branch portal veins.

OUTCOMES

The patient's liver function and the stent patency period were improved. More importantly, the patient had an acceptable survival time.

LESSONS

A Y-configuration stent makes it possible to treat tumor thrombosis in portal vein branches (PVBs). However, the long-term curative effects of Y-configuration stents need to be verified.

摘要

理论依据

目前,肝细胞癌(HCC)合并门静脉癌栓(PVTT)的治疗是一项挑战。据报道,经皮穿刺血管内植入碘-125(I)粒子链和支架可有效治疗伴有肿瘤血栓的HCC。然而,事实证明它仅适用于门静脉主干(MPV)血栓。

患者情况

一名42岁男性患者因右上腹腹胀2周,无腹痛、恶心或呕吐前来我院就诊。该患者有20年的乙型肝炎病毒感染史。

诊断

经过全面评估,患者被诊断为原发性HCC,门静脉主干和分支均有肿瘤血栓。

干预措施

我们采用Y形支架联合I粒子链治疗门静脉主干和分支的肿瘤血栓。

结果

患者的肝功能和支架通畅时间得到改善。更重要的是,患者有可接受的生存时间。

经验教训

Y形支架使治疗门静脉分支(PVB)的肿瘤血栓成为可能。然而,Y形支架的长期疗效有待验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63d1/5704838/8b831864a8e3/medi-96-e8660-g001.jpg

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