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妊娠合并肺泡软部肉瘤伴多发脑和肺转移:一例报告及文献复习

Alveolar soft part sarcoma with multiple brain and lung metastases in pregnancy: A case report and literature review.

作者信息

Wang Yubo, Cui Jiayue, Yan Xu, Jin Rihua, Hong Xinyu

机构信息

aDepartment of Neurosurgery, First Hospital of Jilin University bDepartment of Histology and Embryology, College of Basic Medical Sciences, Jilin University cDepartment of Pathology, First Hospital of Jilin University, Changchun, Jilin, P.R. China.

出版信息

Medicine (Baltimore). 2017 Nov;96(46):e8790. doi: 10.1097/MD.0000000000008790.

Abstract

RATIONAL

Alveolar soft part sarcomas (ASPSs) with multiple brain metastases in pregnancy is a rare entity.

PATIENT CONCERNS

We report our experience with a 19-year-old pregnant woman who presented with intermittent headaches and vomiting at 38 weeks gestation.

DIAGNOSES

The patient was initially diagnosed as brain metastasis according to computed tomography and magnetic resonance imaging (MRI) imaging.

INTERVENTIONS

Cesarean section and craniotomy (complete resection of both brain metastatic lesions) was performed sequentially.

OUTCOMES

A healthy baby girl was delivered safely and no neonatal malformations were found. Histological analysis confirmed the diagnosis of ASPS. Follow-up MRI performed 10 months after surgery revealed no residual tumor or signs of recurrence.

LESSONS

We report a case of ASPS with multiple brain and lung metastases in a pregnant woman. We recommend timely MRI examination for diagnosis and have discussed the approach to the treatment of pregnant women with brain metastasis.

摘要

理论依据

妊娠合并多发脑转移的肺泡软组织肉瘤(ASPS)是一种罕见的疾病。

患者情况

我们报告了一名19岁孕妇的病例,她在妊娠38周时出现间歇性头痛和呕吐。

诊断

根据计算机断层扫描和磁共振成像(MRI)检查,患者最初被诊断为脑转移。

干预措施

依次进行了剖宫产和开颅手术(完整切除两个脑转移瘤)。

结果

安全产下一名健康女婴,未发现新生儿畸形。组织学分析确诊为ASPS。术后10个月的随访MRI显示无残留肿瘤或复发迹象。

经验教训

我们报告了一例孕妇发生多发脑和肺转移的ASPS病例。我们建议及时进行MRI检查以明确诊断,并讨论了脑转移孕妇的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c55/5704884/7138c6ee1d12/medi-96-e8790-g001.jpg

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