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1例重度甲型血友病患者全膝关节置换术中腘动脉损伤的开放修复:病例报告及文献复习

Open repair of intraoperative popliteal artery injury during total knee arthroplasty in a patient with severe hemophilia A: A case report and literature review.

作者信息

Feng Bin, Xiao Ke, Shao Jiang, Fan Yu, Weng Xisheng

机构信息

aDepartment of Orthopaedic Surgery, Peking Union Medical College Hospital bDepartment of Vascular Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China.

出版信息

Medicine (Baltimore). 2017 Nov;96(46):e8791. doi: 10.1097/MD.0000000000008791.

Abstract

RATIONALE

Arterial injuries during total knee arthroplasty (TKA) though rare may occur. Hemophilia may further challenge the management of such injury.

PATIENT CONCERNS

A 48-year-old male patient with severe hemophilia type A and stiff knee arthropathy underwent bilateral TKAs. Left popliteal artery injury was detected at the end of the left TKA.

DIAGNOSES

Urgent angiography confirmed the diagnosis of the left popliteal artery transection.

INTERVENTIONS

With clotting factor VIII replacement treatment, open repair was performed by end-to-end vascular bypass with the autograft of the large saphenous vein. No anticoagulant and antiplatelet treatment was administered postoperatively. Doses of the factor VIII were decreased step by step postoperatively.

OUTCOMES

Left lower limb was reperfused 4 hours after the onset of the ischemia. The patient recovered uneventfully. Postoperative Doppler examination showed the left popliteal artery remained patent.

LESSONS

The hemophilia may endanger the patients to higher risk of arterial injury during TKA because of the severe deformity and fibrosis around knee joint. For the hemophilia patients, with rational coagulation factor replacement therapy, open repair with autograft was an effective revascularization procedure for artery injury.

摘要

理论依据

全膝关节置换术(TKA)期间动脉损伤虽罕见但仍可能发生。血友病可能会给此类损伤的处理带来更大挑战。

患者情况

一名48岁患有重度甲型血友病和膝关节僵硬性关节病的男性患者接受了双侧全膝关节置换术。在左侧全膝关节置换术结束时发现左侧腘动脉损伤。

诊断

紧急血管造影确诊为左侧腘动脉横断。

干预措施

通过大隐静脉自体移植进行端到端血管搭桥,在凝血因子VIII替代治疗的情况下进行开放修复。术后未给予抗凝和抗血小板治疗。术后逐步减少因子VIII的剂量。

结果

缺血发生后4小时左下肢恢复灌注。患者恢复顺利。术后多普勒检查显示左侧腘动脉保持通畅。

经验教训

由于膝关节周围严重畸形和纤维化,血友病可能使患者在全膝关节置换术期间面临更高的动脉损伤风险。对于血友病患者,通过合理的凝血因子替代治疗,自体移植开放修复是治疗动脉损伤的有效血管重建方法。

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